N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria

ABSTRACT J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of...

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Autores principales:	Gerald L. Newton, Mamta Rawat
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	Chlorobium N-methyl-bacillithiol anaerobes bacillithiol glutathione thiols Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/e18482a661334b169f77be8d0bb8d172
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id	oai:doaj.org-article:e18482a661334b169f77be8d0bb8d172
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spelling	oai:doaj.org-article:e18482a661334b169f77be8d0bb8d1722021-11-15T15:55:14ZN-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria10.1128/mBio.02634-182150-7511https://doaj.org/article/e18482a661334b169f77be8d0bb8d1722019-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02634-18https://doaj.org/toc/2150-7511ABSTRACT J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S-adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria.Gerald L. NewtonMamta RawatAmerican Society for MicrobiologyarticleChlorobiumN-methyl-bacillithiolanaerobesbacillithiolglutathionethiolsMicrobiologyQR1-502ENmBio, Vol 10, Iss 1 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chlorobium N-methyl-bacillithiol anaerobes bacillithiol glutathione thiols Microbiology QR1-502
spellingShingle	Chlorobium N-methyl-bacillithiol anaerobes bacillithiol glutathione thiols Microbiology QR1-502 Gerald L. Newton Mamta Rawat N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
description	ABSTRACT J. Hiras, S. V. Sharma, V. Raman, R. A. J. Tinson, et al. (mBio 9:e01603-18, 2018, https://doi.org/10.1128/mBio.01603-18) report on the identification of a novel thiol, N-methyl-bacillithiol (N-Me-BSH), in the green sulfur bacterium Chlorobium tepidum. In N-methyl-bacillithiol, the amine of the cysteine is methylated by a novel S-adenosylmethioneine transferase designated N-methyl-bacillithiol synthase A (NmbA). The Hiras et al. study is significant because it is the first report of the presence of N-Me-BSH in anaerobic bacteria.
format	article
author	Gerald L. Newton Mamta Rawat
author_facet	Gerald L. Newton Mamta Rawat
author_sort	Gerald L. Newton
title	N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_short	N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_full	N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_fullStr	N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_full_unstemmed	N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria
title_sort	n-methyl-bacillithiol, a novel thiol from anaerobic bacteria
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/e18482a661334b169f77be8d0bb8d172
work_keys_str_mv	AT geraldlnewton nmethylbacillithiolanovelthiolfromanaerobicbacteria AT mamtarawat nmethylbacillithiolanovelthiolfromanaerobicbacteria
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N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria

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