Hypertension, BMI, and cardiovascular and cerebrovascular diseases

Hypertension is associated with body mass index (BMI) and cardiovascular and cerebrovascular diseases (CCDs). Whether hypertension modifies the relationship between BMI and CCDs is still unclear. We examined the association between BMI and CCDs and tested whether effect measure modification was pres...

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Autores principales:	Qiao Wenjing, Zhang Xinyi, Kan Bo, Vuong Ann M., Xue Shanshan, Zhang Yuzheng, Li Binbin, Zhao Qianqian, Guo Dingjie, Shen Xue, Yang Shuman
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	cardiovascular and cerebrovascular diseases body mass index hypertension Medicine R
Acceso en línea:	https://doaj.org/article/e185b53ae34d43beaf5ead10bd0ced04
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spelling	oai:doaj.org-article:e185b53ae34d43beaf5ead10bd0ced042021-12-05T14:10:53ZHypertension, BMI, and cardiovascular and cerebrovascular diseases2391-546310.1515/med-2021-0014https://doaj.org/article/e185b53ae34d43beaf5ead10bd0ced042021-01-01T00:00:00Zhttps://doi.org/10.1515/med-2021-0014https://doaj.org/toc/2391-5463Hypertension is associated with body mass index (BMI) and cardiovascular and cerebrovascular diseases (CCDs). Whether hypertension modifies the relationship between BMI and CCDs is still unclear. We examined the association between BMI and CCDs and tested whether effect measure modification was present by hypertension. We identified a population-based sample of 3,942 participants in Shuncheng, Fushun, Liaoning, China. Hypertension was defined as any past use of antihypertensive medication or having a measured systolic/diastolic blood pressure ≥130/80 mm Hg. BMI was calculated from measured body weight and body height. Data on diagnosed CCDs were self-reported and validated in the medical records. We used logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations between BMI and CCDs. Higher BMI was associated with increased odds of having CCDs (OR = 1.19, 95% CI: 1.07–1.31). This association was significantly modified by hypertension (P for interaction <0.001), with positive associations observed among hypertensive individuals (OR = 1.28, 95% CI: 1.14–1.42). Age, sex, and diabetic status did not modify the relationship between BMI and CCDs (all P for interaction >0.10). Although higher BMI was associated with increased odds of CCDs, the relationship was mainly limited to hypertensive patients.Qiao WenjingZhang XinyiKan BoVuong Ann M.Xue ShanshanZhang YuzhengLi BinbinZhao QianqianGuo DingjieShen XueYang ShumanDe Gruyterarticlecardiovascular and cerebrovascular diseasesbody mass indexhypertensionMedicineRENOpen Medicine, Vol 16, Iss 1, Pp 149-155 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiovascular and cerebrovascular diseases body mass index hypertension Medicine R
spellingShingle	cardiovascular and cerebrovascular diseases body mass index hypertension Medicine R Qiao Wenjing Zhang Xinyi Kan Bo Vuong Ann M. Xue Shanshan Zhang Yuzheng Li Binbin Zhao Qianqian Guo Dingjie Shen Xue Yang Shuman Hypertension, BMI, and cardiovascular and cerebrovascular diseases
description	Hypertension is associated with body mass index (BMI) and cardiovascular and cerebrovascular diseases (CCDs). Whether hypertension modifies the relationship between BMI and CCDs is still unclear. We examined the association between BMI and CCDs and tested whether effect measure modification was present by hypertension. We identified a population-based sample of 3,942 participants in Shuncheng, Fushun, Liaoning, China. Hypertension was defined as any past use of antihypertensive medication or having a measured systolic/diastolic blood pressure ≥130/80 mm Hg. BMI was calculated from measured body weight and body height. Data on diagnosed CCDs were self-reported and validated in the medical records. We used logistic regression models to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for associations between BMI and CCDs. Higher BMI was associated with increased odds of having CCDs (OR = 1.19, 95% CI: 1.07–1.31). This association was significantly modified by hypertension (P for interaction <0.001), with positive associations observed among hypertensive individuals (OR = 1.28, 95% CI: 1.14–1.42). Age, sex, and diabetic status did not modify the relationship between BMI and CCDs (all P for interaction >0.10). Although higher BMI was associated with increased odds of CCDs, the relationship was mainly limited to hypertensive patients.
format	article
author	Qiao Wenjing Zhang Xinyi Kan Bo Vuong Ann M. Xue Shanshan Zhang Yuzheng Li Binbin Zhao Qianqian Guo Dingjie Shen Xue Yang Shuman
author_facet	Qiao Wenjing Zhang Xinyi Kan Bo Vuong Ann M. Xue Shanshan Zhang Yuzheng Li Binbin Zhao Qianqian Guo Dingjie Shen Xue Yang Shuman
author_sort	Qiao Wenjing
title	Hypertension, BMI, and cardiovascular and cerebrovascular diseases
title_short	Hypertension, BMI, and cardiovascular and cerebrovascular diseases
title_full	Hypertension, BMI, and cardiovascular and cerebrovascular diseases
title_fullStr	Hypertension, BMI, and cardiovascular and cerebrovascular diseases
title_full_unstemmed	Hypertension, BMI, and cardiovascular and cerebrovascular diseases
title_sort	hypertension, bmi, and cardiovascular and cerebrovascular diseases
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/e185b53ae34d43beaf5ead10bd0ced04
work_keys_str_mv	AT qiaowenjing hypertensionbmiandcardiovascularandcerebrovasculardiseases AT zhangxinyi hypertensionbmiandcardiovascularandcerebrovasculardiseases AT kanbo hypertensionbmiandcardiovascularandcerebrovasculardiseases AT vuongannm hypertensionbmiandcardiovascularandcerebrovasculardiseases AT xueshanshan hypertensionbmiandcardiovascularandcerebrovasculardiseases AT zhangyuzheng hypertensionbmiandcardiovascularandcerebrovasculardiseases AT libinbin hypertensionbmiandcardiovascularandcerebrovasculardiseases AT zhaoqianqian hypertensionbmiandcardiovascularandcerebrovasculardiseases AT guodingjie hypertensionbmiandcardiovascularandcerebrovasculardiseases AT shenxue hypertensionbmiandcardiovascularandcerebrovasculardiseases AT yangshuman hypertensionbmiandcardiovascularandcerebrovasculardiseases
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Hypertension, BMI, and cardiovascular and cerebrovascular diseases

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