The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Abstract There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we inves...

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Autores principales: Andrew J. McKenzie, Stephanie R. Hicks, Kathryn V. Svec, Hannah Naughton, Zöe L. Edmunds, Alan K. Howe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e188616ed8974641a305dd3aa2218f57
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