Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

Type II alveolar cells play central roles in multiple aspects of lung biology. Here the authors show that type II alveolar cells also constitutively express MHCII, exhibit limited MHCII antigen presentation capacity, and are a component of the host response to respiratory viral infection.

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Autores principales:	Sushila A. Toulmin, Chaitali Bhadiadra, Andrew J. Paris, Jeffrey H. Lin, Jeremy Katzen, Maria C. Basil, Edward E. Morrisey, G. Scott Worthen, Laurence C. Eisenlohr
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e19c792b6eed4c79a384d45bab80f5de
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spelling	oai:doaj.org-article:e19c792b6eed4c79a384d45bab80f5de2021-12-02T16:32:13ZType II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation10.1038/s41467-021-23619-62041-1723https://doaj.org/article/e19c792b6eed4c79a384d45bab80f5de2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23619-6https://doaj.org/toc/2041-1723Type II alveolar cells play central roles in multiple aspects of lung biology. Here the authors show that type II alveolar cells also constitutively express MHCII, exhibit limited MHCII antigen presentation capacity, and are a component of the host response to respiratory viral infection.Sushila A. ToulminChaitali BhadiadraAndrew J. ParisJeffrey H. LinJeremy KatzenMaria C. BasilEdward E. MorriseyG. Scott WorthenLaurence C. EisenlohrNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sushila A. Toulmin Chaitali Bhadiadra Andrew J. Paris Jeffrey H. Lin Jeremy Katzen Maria C. Basil Edward E. Morrisey G. Scott Worthen Laurence C. Eisenlohr Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
description	Type II alveolar cells play central roles in multiple aspects of lung biology. Here the authors show that type II alveolar cells also constitutively express MHCII, exhibit limited MHCII antigen presentation capacity, and are a component of the host response to respiratory viral infection.
format	article
author	Sushila A. Toulmin Chaitali Bhadiadra Andrew J. Paris Jeffrey H. Lin Jeremy Katzen Maria C. Basil Edward E. Morrisey G. Scott Worthen Laurence C. Eisenlohr
author_facet	Sushila A. Toulmin Chaitali Bhadiadra Andrew J. Paris Jeffrey H. Lin Jeremy Katzen Maria C. Basil Edward E. Morrisey G. Scott Worthen Laurence C. Eisenlohr
author_sort	Sushila A. Toulmin
title	Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
title_short	Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
title_full	Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
title_fullStr	Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
title_full_unstemmed	Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
title_sort	type ii alveolar cell mhcii improves respiratory viral disease outcomes while exhibiting limited antigen presentation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e19c792b6eed4c79a384d45bab80f5de
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Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

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