Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
Type II alveolar cells play central roles in multiple aspects of lung biology. Here the authors show that type II alveolar cells also constitutively express MHCII, exhibit limited MHCII antigen presentation capacity, and are a component of the host response to respiratory viral infection.
Guardado en:
Autores principales: | Sushila A. Toulmin, Chaitali Bhadiadra, Andrew J. Paris, Jeffrey H. Lin, Jeremy Katzen, Maria C. Basil, Edward E. Morrisey, G. Scott Worthen, Laurence C. Eisenlohr |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e19c792b6eed4c79a384d45bab80f5de |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Standard screening methods underreport AAV-mediated transduction and gene editing
por: Jonathan F. Lang, et al.
Publicado: (2019) -
Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment
por: Justin A. Spanier, et al.
Publicado: (2016) -
Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density
por: Chen-Hao Yeh, et al.
Publicado: (2018) -
Differentiation at the MHCIIα and Cath2 loci in sympatric Salvelinus alpinus resource morphs in Lake Thingvallavatn.
por: Kalina H Kapralova, et al.
Publicado: (2013) -
A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation
por: Michael C Kiritsy, et al.
Publicado: (2021)