SAMHD1 Regulates Human Papillomavirus 16-Induced Cell Proliferation and Viral Replication during Differentiation of Keratinocytes

ABSTRACT Human papillomaviruses induce a host of anogenital cancers, as well as oropharyngeal cancer (HPV+OPC); human papillomavirus 16 (HPV16) is causative in around 90% of HPV+OPC cases. Using telomerase reverse transcriptase (TERT) immortalized foreskin keratinocytes (N/Tert-1), we have identifie...

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Autores principales: Claire D. James, Apurva T. Prabhakar, Raymonde Otoa, Michael R. Evans, Xu Wang, Molly L. Bristol, Kun Zhang, Renfeng Li, Iain M. Morgan
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/e19dd57447874452a7dbf5de97248421
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