RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis

RNA-binding protein IGF2BP2 enhances circ_0000745 abundancy and promotes aggressiveness and stemness of ovarian cancer cells via the microRNA-3187-3p/ERBB4/PI3K/AKT axis

Abstract Background Circular RNAs (circRNAs) are increasingly recognized as important regulators in cancer including ovarian cancer (OC). This work focuses on the effects of circ_0000745 on the OC development of and molecules involved. Methods Expression of circ_0000745 in collected OC tissues and t...

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Autores principales: Shengtan Wang, Zaihong Li, Genhai Zhu, Lan Hong, Chunyan Hu, Kang Wang, Kaiying Cui, Chunbo Hao
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Ovarian cancer
IGF2BP2
circ_0000745
miR-3187-3p
ERBB4
PI3K/AKT
Gynecology and obstetrics
RG1-991
Acceso en línea:https://doaj.org/article/e1a6d3ccbb914c019dddc850b358e9e8
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