Transcription shapes genome-wide histone acetylation patterns

Histone acetylation is a ubiquitous hallmark of transcription. Here the authors provide evidence that the majority of histone acetylation is dependent on transcription, specifically due to the requirement of RNAPII for the recruitment and activity of histone acetyltransferases.

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Detalles Bibliográficos
Autores principales: Benjamin J. E. Martin, Julie Brind’Amour, Anastasia Kuzmin, Kristoffer N. Jensen, Zhen Cheng Liu, Matthew Lorincz, LeAnn J. Howe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e1ac767224d040cd8a4977701af65c0d
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Sumario:Histone acetylation is a ubiquitous hallmark of transcription. Here the authors provide evidence that the majority of histone acetylation is dependent on transcription, specifically due to the requirement of RNAPII for the recruitment and activity of histone acetyltransferases.