Transcription shapes genome-wide histone acetylation patterns
Histone acetylation is a ubiquitous hallmark of transcription. Here the authors provide evidence that the majority of histone acetylation is dependent on transcription, specifically due to the requirement of RNAPII for the recruitment and activity of histone acetyltransferases.
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Nature Portfolio
2021
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oai:doaj.org-article:e1ac767224d040cd8a4977701af65c0d2021-12-02T14:01:15ZTranscription shapes genome-wide histone acetylation patterns10.1038/s41467-020-20543-z2041-1723https://doaj.org/article/e1ac767224d040cd8a4977701af65c0d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20543-zhttps://doaj.org/toc/2041-1723Histone acetylation is a ubiquitous hallmark of transcription. Here the authors provide evidence that the majority of histone acetylation is dependent on transcription, specifically due to the requirement of RNAPII for the recruitment and activity of histone acetyltransferases.Benjamin J. E. MartinJulie Brind’AmourAnastasia KuzminKristoffer N. JensenZhen Cheng LiuMatthew LorinczLeAnn J. HoweNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
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Science Q Benjamin J. E. Martin Julie Brind’Amour Anastasia Kuzmin Kristoffer N. Jensen Zhen Cheng Liu Matthew Lorincz LeAnn J. Howe Transcription shapes genome-wide histone acetylation patterns |
description |
Histone acetylation is a ubiquitous hallmark of transcription. Here the authors provide evidence that the majority of histone acetylation is dependent on transcription, specifically due to the requirement of RNAPII for the recruitment and activity of histone acetyltransferases. |
format |
article |
author |
Benjamin J. E. Martin Julie Brind’Amour Anastasia Kuzmin Kristoffer N. Jensen Zhen Cheng Liu Matthew Lorincz LeAnn J. Howe |
author_facet |
Benjamin J. E. Martin Julie Brind’Amour Anastasia Kuzmin Kristoffer N. Jensen Zhen Cheng Liu Matthew Lorincz LeAnn J. Howe |
author_sort |
Benjamin J. E. Martin |
title |
Transcription shapes genome-wide histone acetylation patterns |
title_short |
Transcription shapes genome-wide histone acetylation patterns |
title_full |
Transcription shapes genome-wide histone acetylation patterns |
title_fullStr |
Transcription shapes genome-wide histone acetylation patterns |
title_full_unstemmed |
Transcription shapes genome-wide histone acetylation patterns |
title_sort |
transcription shapes genome-wide histone acetylation patterns |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/e1ac767224d040cd8a4977701af65c0d |
work_keys_str_mv |
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1718392232428437504 |