The Typhoid Toxin Produced by the Nontyphoidal <italic toggle="yes">Salmonella enterica</italic> Serotype Javiana Is Required for Induction of a DNA Damage Response <italic toggle="yes">In Vitro</italic> and Systemic Spread <italic toggle="yes">In Vivo</italic>

The Typhoid Toxin Produced by the Nontyphoidal <italic toggle="yes">Salmonella enterica</italic> Serotype Javiana Is Required for Induction of a DNA Damage Response <italic toggle="yes">In Vitro</italic> and Systemic Spread <italic toggle="yes">In Vivo</italic>

ABSTRACT The Salmonella cytolethal distending toxin (S-CDT), first described as the “typhoid toxin” in Salmonella enterica subsp. enterica serotype Typhi, induces DNA damage in eukaryotic cells. Recent studies have shown that more than 40 nontyphoidal Salmonella (NTS) serotypes carry genes that enco...

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Autores principales: Rachel A. Miller, Michael I. Betteken, Xiaodong Guo, Craig Altier, Gerald E. Duhamel, Martin Wiedmann
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
DNA damage
Salmonella
nontyphoidal
typhoid toxin
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e1bb783091be41a0bd0d214522588a39
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