Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer
Silvia Liu et al. present LoopSeq, a synthetic long-read sequencing method that generates accurate long-read transcriptome data from short Illumina reads. As an example of possible applications, they use LoopSeq to investigate differential isoform expression, isoform-specific single nucleotide varia...
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Main Authors: | Silvia Liu, Indira Wu, Yan-Ping Yu, Michael Balamotis, Baoguo Ren, Tuval Ben Yehezkel, Jian-Hua Luo |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/e1cb04e6a8a1480383f9180ac1ea8876 |
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