Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

γδ T cells are generally considered innate‐like lymphocytes. Here the authors sequence human γδ T cell receptors (TCR) to show focusing of the private Vδ1 TCR repertoire, suggesting that, unlike Vδ2 T cells, the Vδ1 T cell compartment has adaptive attributes.

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Autores principales:	Martin S. Davey, Carrie R. Willcox, Stephen P. Joyce, Kristin Ladell, Sofya A. Kasatskaya, James E. McLaren, Stuart Hunter, Mahboob Salim, Fiyaz Mohammed, David A. Price, Dmitriy M. Chudakov, Benjamin E. Willcox
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e1ccfb7e084e42f698fa39ef31fcea3d
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spelling	oai:doaj.org-article:e1ccfb7e084e42f698fa39ef31fcea3d2021-12-02T17:06:30ZClonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance10.1038/ncomms147602041-1723https://doaj.org/article/e1ccfb7e084e42f698fa39ef31fcea3d2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14760https://doaj.org/toc/2041-1723γδ T cells are generally considered innate‐like lymphocytes. Here the authors sequence human γδ T cell receptors (TCR) to show focusing of the private Vδ1 TCR repertoire, suggesting that, unlike Vδ2 T cells, the Vδ1 T cell compartment has adaptive attributes.Martin S. DaveyCarrie R. WillcoxStephen P. JoyceKristin LadellSofya A. KasatskayaJames E. McLarenStuart HunterMahboob SalimFiyaz MohammedDavid A. PriceDmitriy M. ChudakovBenjamin E. WillcoxNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martin S. Davey Carrie R. Willcox Stephen P. Joyce Kristin Ladell Sofya A. Kasatskaya James E. McLaren Stuart Hunter Mahboob Salim Fiyaz Mohammed David A. Price Dmitriy M. Chudakov Benjamin E. Willcox Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
description	γδ T cells are generally considered innate‐like lymphocytes. Here the authors sequence human γδ T cell receptors (TCR) to show focusing of the private Vδ1 TCR repertoire, suggesting that, unlike Vδ2 T cells, the Vδ1 T cell compartment has adaptive attributes.
format	article
author	Martin S. Davey Carrie R. Willcox Stephen P. Joyce Kristin Ladell Sofya A. Kasatskaya James E. McLaren Stuart Hunter Mahboob Salim Fiyaz Mohammed David A. Price Dmitriy M. Chudakov Benjamin E. Willcox
author_facet	Martin S. Davey Carrie R. Willcox Stephen P. Joyce Kristin Ladell Sofya A. Kasatskaya James E. McLaren Stuart Hunter Mahboob Salim Fiyaz Mohammed David A. Price Dmitriy M. Chudakov Benjamin E. Willcox
author_sort	Martin S. Davey
title	Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
title_short	Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
title_full	Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
title_fullStr	Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
title_full_unstemmed	Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
title_sort	clonal selection in the human vδ1 t cell repertoire indicates γδ tcr-dependent adaptive immune surveillance
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e1ccfb7e084e42f698fa39ef31fcea3d
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Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance

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