Complement Susceptibility in Relation to Genome Sequence of Recent <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates from Thai Hospitals

Complement Susceptibility in Relation to Genome Sequence of Recent <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates from Thai Hospitals

ABSTRACT The capacity to resist the bactericidal action of complement (C′) is a strong but poorly understood virulence trait in Klebsiella spp. Killing requires activation of one or more C′ pathways, assembly of C5b-9 membrane attack complexes (MACs) on the surface of the outer membrane (OM), and pe...

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Bibliographic Details
Main Authors: Jessica Loraine, Eva Heinz, Jessica De Sousa Almeida, Oleksandr Milevskyy, Supayang P. Voravuthikunchai, Potjanee Srimanote, Pattarachai Kiratisin, Nicholas R. Thomson, Peter W. Taylor
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Klebsiella pneumoniae
complement resistance
lipopolysaccharide
polysaccharide capsules
whole-genome sequencing
Microbiology
QR1-502
Online Access:https://doaj.org/article/e1cda7f719f248bd8f2faf90722ce603
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