Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from <named-content content-type="genus-species">Fusarium graminearum</named-content> PH-1

Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from <named-content content-type="genus-species">Fusarium graminearum</named-content> PH-1

ABSTRACT Total biosynthesis or whole-cell biocatalytic production of sulfated small molecules relies on the discovery and implementation of appropriate sulfotransferase enzymes. Although fungi are prominent biocatalysts and have been used to sulfate drug-like phenolics, no gene encoding a sulfotrans...

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Autores principales: Linan Xie, Dongliang Xiao, Xiaojing Wang, Chen Wang, Jing Bai, Qun Yue, Haitao Yue, Ye Li, István Molnár, Yuquan Xu, Liwen Zhang
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Fusarium
combinatorial biosynthesis
phenolic sulfotransferase
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e1cfc2e976144483ae7c2f995219c827
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