Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool

Background: Intestinal ultrasound is emerging as a non-invasive tool for monitoring disease activity in inflammatory bowel disease patients due to its low cost, excellent safety profile, and availability. Herein, we comprehensively review the role of intestinal ultrasound in the management of these...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Catarina Frias-Gomes, Joana Torres, Carolina Palmela
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	intestinal ultrasound diagnosis disease activity monitoring therapy response point-of-care Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/e1d67abdac9142328db4f6092c29a874
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e1d67abdac9142328db4f6092c29a874
record_format	dspace
spelling	oai:doaj.org-article:e1d67abdac9142328db4f6092c29a8742021-12-02T12:40:23ZIntestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool2341-45452387-195410.1159/000520212https://doaj.org/article/e1d67abdac9142328db4f6092c29a8742021-11-01T00:00:00Zhttps://www.karger.com/Article/FullText/520212https://doaj.org/toc/2341-4545https://doaj.org/toc/2387-1954Background: Intestinal ultrasound is emerging as a non-invasive tool for monitoring disease activity in inflammatory bowel disease patients due to its low cost, excellent safety profile, and availability. Herein, we comprehensively review the role of intestinal ultrasound in the management of these patients. Summary: Intestinal ultrasound has a good accuracy in the diagnosis of Crohn’s disease, as well as in the assessment of disease activity, extent, and evaluating disease-related complications, namely strictures, fistulae, and abscesses. Even though not fully validated, several scores have been developed to assess disease activity using ultrasound. Importantly, intestinal ultrasound can also be used to assess response to treatment. Changes in ultrasonographic parameters are observed as early as 4 weeks after treatment initiation and persist during short- and long-term follow-up. Additionally, Crohn’s disease patients with no ultrasound improvement seem to be at a higher risk of therapy intensification, need for steroids, hospitalisation, or even surgery. Similarly to Crohn’s disease, intestinal ultrasound has a good performance in the diagnosis, activity, and disease extent assessment in ulcerative colitis patients. In fact, in patients with severe acute colitis, higher bowel wall thickness at admission is associated with the need for salvage therapy and the absence of a significant decrease in this parameter may predict the need for colectomy. Short-term data also evidence the role of intestinal ultrasound in evaluating therapy response, with ultrasound changes observed after 2 weeks of treatment and significant improvement after 12 weeks of follow-up in ulcerative colitis. Key Messages: Intestinal ultrasound is a valuable tool to assess disease activity and complications, and to monitor response to therapy. Even though longer prospective data are warranted, intestinal ultrasound may lead to a change in the paradigm of inflammatory bowel disease management as it can be used in a point-of-care setting, enabling earlier intervention if needed.Catarina Frias-GomesJoana TorresCarolina PalmelaKarger Publishersarticleintestinal ultrasounddiagnosisdisease activitymonitoringtherapy responsepoint-of-careDiseases of the digestive system. GastroenterologyRC799-869ENGE: Portuguese Journal of Gastroenterology, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	intestinal ultrasound diagnosis disease activity monitoring therapy response point-of-care Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	intestinal ultrasound diagnosis disease activity monitoring therapy response point-of-care Diseases of the digestive system. Gastroenterology RC799-869 Catarina Frias-Gomes Joana Torres Carolina Palmela Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool
description	Background: Intestinal ultrasound is emerging as a non-invasive tool for monitoring disease activity in inflammatory bowel disease patients due to its low cost, excellent safety profile, and availability. Herein, we comprehensively review the role of intestinal ultrasound in the management of these patients. Summary: Intestinal ultrasound has a good accuracy in the diagnosis of Crohn’s disease, as well as in the assessment of disease activity, extent, and evaluating disease-related complications, namely strictures, fistulae, and abscesses. Even though not fully validated, several scores have been developed to assess disease activity using ultrasound. Importantly, intestinal ultrasound can also be used to assess response to treatment. Changes in ultrasonographic parameters are observed as early as 4 weeks after treatment initiation and persist during short- and long-term follow-up. Additionally, Crohn’s disease patients with no ultrasound improvement seem to be at a higher risk of therapy intensification, need for steroids, hospitalisation, or even surgery. Similarly to Crohn’s disease, intestinal ultrasound has a good performance in the diagnosis, activity, and disease extent assessment in ulcerative colitis patients. In fact, in patients with severe acute colitis, higher bowel wall thickness at admission is associated with the need for salvage therapy and the absence of a significant decrease in this parameter may predict the need for colectomy. Short-term data also evidence the role of intestinal ultrasound in evaluating therapy response, with ultrasound changes observed after 2 weeks of treatment and significant improvement after 12 weeks of follow-up in ulcerative colitis. Key Messages: Intestinal ultrasound is a valuable tool to assess disease activity and complications, and to monitor response to therapy. Even though longer prospective data are warranted, intestinal ultrasound may lead to a change in the paradigm of inflammatory bowel disease management as it can be used in a point-of-care setting, enabling earlier intervention if needed.
format	article
author	Catarina Frias-Gomes Joana Torres Carolina Palmela
author_facet	Catarina Frias-Gomes Joana Torres Carolina Palmela
author_sort	Catarina Frias-Gomes
title	Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool
title_short	Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool
title_full	Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool
title_fullStr	Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool
title_full_unstemmed	Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool
title_sort	intestinal ultrasound in inflammatory bowel disease: a valuable and increasingly important tool
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/e1d67abdac9142328db4f6092c29a874
work_keys_str_mv	AT catarinafriasgomes intestinalultrasoundininflammatoryboweldiseaseavaluableandincreasinglyimportanttool AT joanatorres intestinalultrasoundininflammatoryboweldiseaseavaluableandincreasinglyimportanttool AT carolinapalmela intestinalultrasoundininflammatoryboweldiseaseavaluableandincreasinglyimportanttool
_version_	1718393772553797632

Intestinal Ultrasound in Inflammatory Bowel Disease: A Valuable and Increasingly Important Tool

Ejemplares similares