Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle.

Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle.

Hepatitis C virus (HCV) infection develops into chronicity in 80% of all patients, characterized by persistent low-level replication. To understand how the virus establishes its tightly controlled intracellular RNA replication cycle, we developed the first detailed mathematical model of the initial...

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Detalles Bibliográficos
Autores principales: Marco Binder, Nurgazy Sulaimanov, Diana Clausznitzer, Manuel Schulze, Christian M Hüber, Simon M Lenz, Johannes P Schlöder, Martin Trippler, Ralf Bartenschlager, Volker Lohmann, Lars Kaderali
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/e1dc895e827a4dd7b115633d1eeb9a6a
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