Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent

Plants have been used as traditional medicine since ancient times for treating the diseases, metabolite active compounds from plants have excellent bioactivity, and pharmacological properties from plants are used as skin whitening agent and antioxidant in multiple mechanisms of action. However, thes...

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Autores principales:	Yasmiwar Susilawati, Anis Yohana Chaerunisa, Hesti Purwaningsih
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	phytosome and cosmetic skin antioxidant skin whitening agent Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/e1e4d60103524890b007ed987de74bd6
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spelling	oai:doaj.org-article:e1e4d60103524890b007ed987de74bd62021-11-12T10:17:53ZPhytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent2231-40400976-209410.4103/japtr.JAPTR_100_20https://doaj.org/article/e1e4d60103524890b007ed987de74bd62021-01-01T00:00:00Zhttp://www.japtr.org/article.asp?issn=2231-4040;year=2021;volume=12;issue=4;spage=327;epage=334;aulast=Susilawatihttps://doaj.org/toc/2231-4040https://doaj.org/toc/0976-2094Plants have been used as traditional medicine since ancient times for treating the diseases, metabolite active compounds from plants have excellent bioactivity, and pharmacological properties from plants are used as skin whitening agent and antioxidant in multiple mechanisms of action. However, these compounds have physicochemical limitations in terms of its poor solubility and penetration into the cells membrane. Phytosome drug delivery system can be the primary choice to improve the physicochemical properties, which allows increasing the effectiveness. This review aimed to summarize and discuss the phytosome formulations of potential active compounds as skin whitening agent and skin antioxidant, which obtained from Scopus, PubMed, and Google Scholar databases. We assessed that the main purpose of these phytosome formulations was to improve penetration, stability, and solubility of the active compounds. These studies proved that phytosome formulations can improve the physicochemical characteristics and effectiveness of compounds. The phytosome drug delivery system becomes a promising modification technique for natural compounds due to the ability to improve the physicochemical properties and increase the effectiveness. Phytosome formulation could be the excellent approach for cosmeceutical product with good effectivity in the future.Yasmiwar SusilawatiAnis Yohana ChaerunisaHesti PurwaningsihWolters Kluwer Medknow Publicationsarticlephytosome and cosmeticskin antioxidantskin whitening agentTherapeutics. PharmacologyRM1-950Pharmacy and materia medicaRS1-441ENJournal of Advanced Pharmaceutical Technology & Research, Vol 12, Iss 4, Pp 327-334 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	phytosome and cosmetic skin antioxidant skin whitening agent Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441
spellingShingle	phytosome and cosmetic skin antioxidant skin whitening agent Therapeutics. Pharmacology RM1-950 Pharmacy and materia medica RS1-441 Yasmiwar Susilawati Anis Yohana Chaerunisa Hesti Purwaningsih Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent
description	Plants have been used as traditional medicine since ancient times for treating the diseases, metabolite active compounds from plants have excellent bioactivity, and pharmacological properties from plants are used as skin whitening agent and antioxidant in multiple mechanisms of action. However, these compounds have physicochemical limitations in terms of its poor solubility and penetration into the cells membrane. Phytosome drug delivery system can be the primary choice to improve the physicochemical properties, which allows increasing the effectiveness. This review aimed to summarize and discuss the phytosome formulations of potential active compounds as skin whitening agent and skin antioxidant, which obtained from Scopus, PubMed, and Google Scholar databases. We assessed that the main purpose of these phytosome formulations was to improve penetration, stability, and solubility of the active compounds. These studies proved that phytosome formulations can improve the physicochemical characteristics and effectiveness of compounds. The phytosome drug delivery system becomes a promising modification technique for natural compounds due to the ability to improve the physicochemical properties and increase the effectiveness. Phytosome formulation could be the excellent approach for cosmeceutical product with good effectivity in the future.
format	article
author	Yasmiwar Susilawati Anis Yohana Chaerunisa Hesti Purwaningsih
author_facet	Yasmiwar Susilawati Anis Yohana Chaerunisa Hesti Purwaningsih
author_sort	Yasmiwar Susilawati
title	Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent
title_short	Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent
title_full	Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent
title_fullStr	Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent
title_full_unstemmed	Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent
title_sort	phytosome drug delivery system for natural cosmeceutical compounds: whitening agent and skin antioxidant agent
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/e1e4d60103524890b007ed987de74bd6
work_keys_str_mv	AT yasmiwarsusilawati phytosomedrugdeliverysystemfornaturalcosmeceuticalcompoundswhiteningagentandskinantioxidantagent AT anisyohanachaerunisa phytosomedrugdeliverysystemfornaturalcosmeceuticalcompoundswhiteningagentandskinantioxidantagent AT hestipurwaningsih phytosomedrugdeliverysystemfornaturalcosmeceuticalcompoundswhiteningagentandskinantioxidantagent
_version_	1718431023471001600

Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent

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