Ion-dependent slow protein release from in vivo disintegrating micro-granules

Through the controlled addition of divalent cations, polyhistidine-tagged proteins can be clustered in form of chemically pure and mechanically stable micron-scale particles. Under physiological conditions, these materials act as self-disintegrating protein depots for the progressive release of the...

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Autores principales: Patricia Álamo, Eloi Parladé, Hèctor López-Laguna, Eric Voltà-Durán, Ugutz Unzueta, Esther Vazquez, Ramon Mangues, Antonio Villaverde
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
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Acceso en línea:https://doaj.org/article/e1e64558485743c29d1660000687a2b5
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