Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex

Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while...

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Autores principales: Alireza Chenani, Marta Sabariego, Magdalene I. Schlesiger, Jill K. Leutgeb, Stefan Leutgeb, Christian Leibold
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e1eb1c523e274f00922102f594a261db
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spelling oai:doaj.org-article:e1eb1c523e274f00922102f594a261db2021-12-02T16:57:20ZHippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex10.1038/s41467-019-09280-02041-1723https://doaj.org/article/e1eb1c523e274f00922102f594a261db2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09280-0https://doaj.org/toc/2041-1723Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while replay during the behavioral epoch is reduced.Alireza ChenaniMarta SabariegoMagdalene I. SchlesigerJill K. LeutgebStefan LeutgebChristian LeiboldNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alireza Chenani
Marta Sabariego
Magdalene I. Schlesiger
Jill K. Leutgeb
Stefan Leutgeb
Christian Leibold
Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
description Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while replay during the behavioral epoch is reduced.
format article
author Alireza Chenani
Marta Sabariego
Magdalene I. Schlesiger
Jill K. Leutgeb
Stefan Leutgeb
Christian Leibold
author_facet Alireza Chenani
Marta Sabariego
Magdalene I. Schlesiger
Jill K. Leutgeb
Stefan Leutgeb
Christian Leibold
author_sort Alireza Chenani
title Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
title_short Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
title_full Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
title_fullStr Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
title_full_unstemmed Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
title_sort hippocampal ca1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e1eb1c523e274f00922102f594a261db
work_keys_str_mv AT alirezachenani hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex
AT martasabariego hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex
AT magdaleneischlesiger hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex
AT jillkleutgeb hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex
AT stefanleutgeb hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex
AT christianleibold hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex
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