Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex
Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while...
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Nature Portfolio
2019
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oai:doaj.org-article:e1eb1c523e274f00922102f594a261db2021-12-02T16:57:20ZHippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex10.1038/s41467-019-09280-02041-1723https://doaj.org/article/e1eb1c523e274f00922102f594a261db2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09280-0https://doaj.org/toc/2041-1723Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while replay during the behavioral epoch is reduced.Alireza ChenaniMarta SabariegoMagdalene I. SchlesigerJill K. LeutgebStefan LeutgebChristian LeiboldNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Alireza Chenani Marta Sabariego Magdalene I. Schlesiger Jill K. Leutgeb Stefan Leutgeb Christian Leibold Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
description |
Medial entorhinal cortex (MEC) is involved in memory processes that entail the replay of sequential firing of hippocampal place cells during rest periods and during behaviour. Here, the authors show that MEC lesioned animals show intact replay after an epoch of rats running on a linear track, while replay during the behavioral epoch is reduced. |
format |
article |
author |
Alireza Chenani Marta Sabariego Magdalene I. Schlesiger Jill K. Leutgeb Stefan Leutgeb Christian Leibold |
author_facet |
Alireza Chenani Marta Sabariego Magdalene I. Schlesiger Jill K. Leutgeb Stefan Leutgeb Christian Leibold |
author_sort |
Alireza Chenani |
title |
Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
title_short |
Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
title_full |
Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
title_fullStr |
Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
title_full_unstemmed |
Hippocampal CA1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
title_sort |
hippocampal ca1 replay becomes less prominent but more rigid without inputs from medial entorhinal cortex |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/e1eb1c523e274f00922102f594a261db |
work_keys_str_mv |
AT alirezachenani hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex AT martasabariego hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex AT magdaleneischlesiger hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex AT jillkleutgeb hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex AT stefanleutgeb hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex AT christianleibold hippocampalca1replaybecomeslessprominentbutmorerigidwithoutinputsfrommedialentorhinalcortex |
_version_ |
1718382595298820096 |