The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment

Background: Hypovitaminosis D, low bone mineral density, non-specific musculoskeletal pain, increased risk of fracture, and periodontal disease were reported in most subjects recruited from the Methadone Maintenance Treatment (MMT) program. This study aimed to determine the relationship between vita...

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Autores principales: Fateme Abdolahzade-Arani, Farzad Kahrizi, Amir Ghaderi, Hamid Reza Banafsheh
Formato: article
Lenguaje:EN
Publicado: Shaheed Beheshti University of Medical Sciences 2021
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Acceso en línea:https://doi.org/10.32598/ijmtfm.v11i3.34968
https://doaj.org/article/e1f4c91df9af481196aa0066b77a3ad4
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spelling oai:doaj.org-article:e1f4c91df9af481196aa0066b77a3ad42021-11-08T08:28:44ZThe Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatmenthttps://doi.org/10.32598/ijmtfm.v11i3.349682251-87622251-8770https://doaj.org/article/e1f4c91df9af481196aa0066b77a3ad42021-08-01T00:00:00Zhttps://journals.sbmu.ac.ir/ijmtfm/article/view/34968https://doaj.org/toc/2251-8762https://doaj.org/toc/2251-8770Background: Hypovitaminosis D, low bone mineral density, non-specific musculoskeletal pain, increased risk of fracture, and periodontal disease were reported in most subjects recruited from the Methadone Maintenance Treatment (MMT) program. This study aimed to determine the relationship between vitamin D levels and the severity of anxiety and depression in patients under MMT. Methods: In a cross-sectional study, serum vitamin D levels were measured among 500 patients under MMT from Kashan Province, Iran. Correlation tests were used to assess the association of vitamin D levels with the severity of anxiety and depression in the explored patients. Results: We found that serum vitamin D levels were positively correlated with the scores of the Beck Depression Inventory (BDI) (r=0.107, P=0.017) and the Beck Anxiety Inventory (BAI) (r=0.129, P=0.004). Additionally, there was a negative correlation between serum vitamin D levels, MMT dosage (r=-0.011, P=0.8), and the duration of MMT (r=-0.017, P=0.7). Conclusion: Our findings demonstrated that serum vitamin D levels were independently correlated with the BDI and BAI scores. Further studies are required to confirm our findings.Fateme Abdolahzade-AraniFarzad KahriziAmir GhaderiHamid Reza BanafshehShaheed Beheshti University of Medical Sciencesarticlevitamin danxietydepressionmethadoneMedicine (General)R5-920Toxicology. PoisonsRA1190-1270ENInternational Journal of Medical Toxicology and Forensic Medicine, Vol 11, Iss 3, p 34968 (2021)
institution DOAJ
collection DOAJ
language EN
topic vitamin d
anxiety
depression
methadone
Medicine (General)
R5-920
Toxicology. Poisons
RA1190-1270
spellingShingle vitamin d
anxiety
depression
methadone
Medicine (General)
R5-920
Toxicology. Poisons
RA1190-1270
Fateme Abdolahzade-Arani
Farzad Kahrizi
Amir Ghaderi
Hamid Reza Banafsheh
The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
description Background: Hypovitaminosis D, low bone mineral density, non-specific musculoskeletal pain, increased risk of fracture, and periodontal disease were reported in most subjects recruited from the Methadone Maintenance Treatment (MMT) program. This study aimed to determine the relationship between vitamin D levels and the severity of anxiety and depression in patients under MMT. Methods: In a cross-sectional study, serum vitamin D levels were measured among 500 patients under MMT from Kashan Province, Iran. Correlation tests were used to assess the association of vitamin D levels with the severity of anxiety and depression in the explored patients. Results: We found that serum vitamin D levels were positively correlated with the scores of the Beck Depression Inventory (BDI) (r=0.107, P=0.017) and the Beck Anxiety Inventory (BAI) (r=0.129, P=0.004). Additionally, there was a negative correlation between serum vitamin D levels, MMT dosage (r=-0.011, P=0.8), and the duration of MMT (r=-0.017, P=0.7). Conclusion: Our findings demonstrated that serum vitamin D levels were independently correlated with the BDI and BAI scores. Further studies are required to confirm our findings.
format article
author Fateme Abdolahzade-Arani
Farzad Kahrizi
Amir Ghaderi
Hamid Reza Banafsheh
author_facet Fateme Abdolahzade-Arani
Farzad Kahrizi
Amir Ghaderi
Hamid Reza Banafsheh
author_sort Fateme Abdolahzade-Arani
title The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
title_short The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
title_full The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
title_fullStr The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
title_full_unstemmed The Relationship Between Vitamin D Levels and the Severity of Anxiety and Depression in Patients Under Methadone Maintenance Treatment
title_sort relationship between vitamin d levels and the severity of anxiety and depression in patients under methadone maintenance treatment
publisher Shaheed Beheshti University of Medical Sciences
publishDate 2021
url https://doi.org/10.32598/ijmtfm.v11i3.34968
https://doaj.org/article/e1f4c91df9af481196aa0066b77a3ad4
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