Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

Abstract In this work, we applied the sequence-based statistical coupling analysis approach to characterize conserved amino acid networks important for biochemical function in the pancreatic-type ribonuclease (ptRNase) superfamily. This superfamily-wide analysis indicates a decomposition of the RNas...

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Auteurs principaux: Chitra Narayanan, Donald Gagné, Kimberly A. Reynolds, Nicolas Doucet
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/e1f69c4e9b494b9dbefb82876d0eca19
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