Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily

Abstract In this work, we applied the sequence-based statistical coupling analysis approach to characterize conserved amino acid networks important for biochemical function in the pancreatic-type ribonuclease (ptRNase) superfamily. This superfamily-wide analysis indicates a decomposition of the RNas...

Full description

Saved in:
Bibliographic Details
Main Authors: Chitra Narayanan, Donald Gagné, Kimberly A. Reynolds, Nicolas Doucet
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/e1f69c4e9b494b9dbefb82876d0eca19
Tags: Add Tag
No Tags, Be the first to tag this record!