ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3

ULK1 Suppresses Osteoclast Differentiation and Bone Resorption via Inhibiting Syk-JNK through DOK3

Bone resorption diseases, including osteoporosis, are usually caused by excessive osteoclastogenesis. Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian serine/threonine kinase, may participate in the regulation of bone homeostasis and osteolytic metastasis. In this study, ULK1 expression...

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Autores principales: Yufeng Zhang, Sheng Zhang, Yi Wang, Zhiqiang Yang, Zhe Chen, Nengqiao Wen, Min Yang, Zan Huang, Yuanlong Xie, Lin Cai
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
Materias:
Cytology
QH573-671
Acceso en línea:https://doaj.org/article/e1f6bf5629c54ffabc9cd3c505c05870
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