Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)

Introduction: The clinical significance of potential drug-drug interactions (pDDIs), especially in the intensive care unit (ICU) manifested mostly as adverse drug reactions. Aim: The goal of this research was to conduct a focus group, in which the participants were decisionmakers in acute ischemic s...

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Autores principales:	Aleksić Dejan Z., Petković Pavle Z., Milosavljević Miloš N., Stefanovic Srđan M., Janković Slobodan M.
Formato:	article
Lenguaje:	EN SR
Publicado:	Srpsko lekarsko drustvo 2021
Materias:	focus delphi stroke drug-drug interactions intensive care unit Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/e1fb27926ce64cfcb42b23f9dc962d46
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spelling	oai:doaj.org-article:e1fb27926ce64cfcb42b23f9dc962d462021-12-05T21:22:02ZFocus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)2334-949210.5937/hpimj2102041Ahttps://doaj.org/article/e1fb27926ce64cfcb42b23f9dc962d462021-01-01T00:00:00Zhttps://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2021/2334-94922102041A.pdfhttps://doaj.org/toc/2334-9492Introduction: The clinical significance of potential drug-drug interactions (pDDIs), especially in the intensive care unit (ICU) manifested mostly as adverse drug reactions. Aim: The goal of this research was to conduct a focus group, in which the participants were decisionmakers in acute ischemic stroke patient treatment. Also, the aim was to reach a consensus, due to the Delphi process, between neurologists and clinical pharmacologists regarding this highly vulnerable group of patients. Material and Methods: In this academic research, so-called applied focus group (the goal was to reach practical decisions) and clinical focus group (determining motives, predeterminations, bias, prejudice and analyzing the behavior leading to a certain outcome) was done. Results: Continuing medical education of neurologists is needed regarding pDDIs and the use of an online pDDIs checker. Certain groups of patients with AIS are at particular risk of exposure to pDDIs. Certain drug groups are more likely to interact with other drugs. Conclusions: Defining medical recommendations/guidelines on evidence base medicine about pDDIs in patients with AIS would significantly contribute to reducing their frequency in this vulnerable patient population.Aleksić Dejan Z.Petković Pavle Z.Milosavljević Miloš N.Stefanovic Srđan M.Janković Slobodan M.Srpsko lekarsko drustvoarticlefocusdelphistrokedrug-drug interactionsintensive care unitTherapeutics. PharmacologyRM1-950ENSRHospital Pharmacology, Vol 8, Iss 2, Pp 1041-1050 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	focus delphi stroke drug-drug interactions intensive care unit Therapeutics. Pharmacology RM1-950
spellingShingle	focus delphi stroke drug-drug interactions intensive care unit Therapeutics. Pharmacology RM1-950 Aleksić Dejan Z. Petković Pavle Z. Milosavljević Miloš N. Stefanovic Srđan M. Janković Slobodan M. Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
description	Introduction: The clinical significance of potential drug-drug interactions (pDDIs), especially in the intensive care unit (ICU) manifested mostly as adverse drug reactions. Aim: The goal of this research was to conduct a focus group, in which the participants were decisionmakers in acute ischemic stroke patient treatment. Also, the aim was to reach a consensus, due to the Delphi process, between neurologists and clinical pharmacologists regarding this highly vulnerable group of patients. Material and Methods: In this academic research, so-called applied focus group (the goal was to reach practical decisions) and clinical focus group (determining motives, predeterminations, bias, prejudice and analyzing the behavior leading to a certain outcome) was done. Results: Continuing medical education of neurologists is needed regarding pDDIs and the use of an online pDDIs checker. Certain groups of patients with AIS are at particular risk of exposure to pDDIs. Certain drug groups are more likely to interact with other drugs. Conclusions: Defining medical recommendations/guidelines on evidence base medicine about pDDIs in patients with AIS would significantly contribute to reducing their frequency in this vulnerable patient population.
format	article
author	Aleksić Dejan Z. Petković Pavle Z. Milosavljević Miloš N. Stefanovic Srđan M. Janković Slobodan M.
author_facet	Aleksić Dejan Z. Petković Pavle Z. Milosavljević Miloš N. Stefanovic Srđan M. Janković Slobodan M.
author_sort	Aleksić Dejan Z.
title	Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
title_short	Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
title_full	Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
title_fullStr	Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
title_full_unstemmed	Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)
title_sort	focus group and delphi process: stroke and potential drug-drug interactions (pddi) in the neurological intensive care unit (nicu)
publisher	Srpsko lekarsko drustvo
publishDate	2021
url	https://doaj.org/article/e1fb27926ce64cfcb42b23f9dc962d46
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Focus group and Delphi process: Stroke and potential drug-drug Interactions (pDDI) in the neurological Intensive Care Unit (NICU)

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