Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis

Abstract Berberine (BBR) has been explored as a potential anti-liver fibrosis agent, but the underlying mechanisms are unknown. In the current study, we aimed to investigate the molecular mechanisms underlying the effect of BBR against liver fibrogenesis in thioacetamide (TAA) and carbon tetrachlori...

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Bibliographic Details
Main Authors: Jiazhi Yi, Shuyun Wu, Siwei Tan, Yunfei Qin, Xing Wang, Jie Jiang, Huiling Liu, Bin Wu
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/e20b2c9dbc22437d8bca7f0f63a74de5
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