Engineering nanoparticles to overcome the mucus barrier for drug delivery: Design, evaluation and state-of-the-art
Mucus is a viscoelastic hydrogel that lubricates and protects mucosal tissues such as the eyes, lung, gastrointestinal tract, and vagina. Nanoparticle-based drug delivery systems (DDSs) can be easily trapped in the mucus network by steric obstruction and/or binding interactions and then are efficien...
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Main Authors: | Chang Liu, Xiaohe Jiang, Yong Gan, Miaorong Yu |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Subjects: | |
Online Access: | https://doaj.org/article/e211f9c5a04e4731a75b512b039d03e8 |
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