ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes.

Only a small percentage of human transcription factors (e.g. those associated with a specific differentiation program) are expressed in a given cell type. Thus, cell fate is mainly determined by cell type-specific silencing of transcription factors that drive different cellular lineages. Several his...

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Auteurs principaux: Seth Frietze, Henriette O'Geen, Kimberly R Blahnik, Victor X Jin, Peggy J Farnham
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/e228ff23de144c23bd678f87016e3721
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