Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila

Direction-selective T4/T5 neurons show layer-specific projections in the fly visual circuit. Examining the mechanisms behind their development, the authors found that a relay of Wnt and Bmp signaling across neuroepithelial domains and transcription factor interactions specify T4/T5 subtype identity.

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Autores principales: Holger Apitz, Iris Salecker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
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Acceso en línea:https://doaj.org/article/e2364de6218e49acb68e9f2751a66319
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spelling oai:doaj.org-article:e2364de6218e49acb68e9f2751a663192021-12-02T14:41:06ZSpatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila10.1038/s41467-018-04592-z2041-1723https://doaj.org/article/e2364de6218e49acb68e9f2751a663192018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04592-zhttps://doaj.org/toc/2041-1723Direction-selective T4/T5 neurons show layer-specific projections in the fly visual circuit. Examining the mechanisms behind their development, the authors found that a relay of Wnt and Bmp signaling across neuroepithelial domains and transcription factor interactions specify T4/T5 subtype identity.Holger ApitzIris SaleckerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Holger Apitz
Iris Salecker
Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila
description Direction-selective T4/T5 neurons show layer-specific projections in the fly visual circuit. Examining the mechanisms behind their development, the authors found that a relay of Wnt and Bmp signaling across neuroepithelial domains and transcription factor interactions specify T4/T5 subtype identity.
format article
author Holger Apitz
Iris Salecker
author_facet Holger Apitz
Iris Salecker
author_sort Holger Apitz
title Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila
title_short Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila
title_full Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila
title_fullStr Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila
title_full_unstemmed Spatio-temporal relays control layer identity of direction-selective neuron subtypes in Drosophila
title_sort spatio-temporal relays control layer identity of direction-selective neuron subtypes in drosophila
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/e2364de6218e49acb68e9f2751a66319
work_keys_str_mv AT holgerapitz spatiotemporalrelayscontrollayeridentityofdirectionselectiveneuronsubtypesindrosophila
AT irissalecker spatiotemporalrelayscontrollayeridentityofdirectionselectiveneuronsubtypesindrosophila
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