Unsupervised Domain Adaptation Network With Category-Centric Prototype Aligner for Biomedical Image Segmentation

With the widespread success of deep learning in biomedical image segmentation, domain shift becomes a critical and challenging problem, as the gap between two domains can severely affect model performance when deployed to unseen data with heterogeneous features. To alleviate this problem, we present...

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Detalles Bibliográficos
Autores principales: Ping Gong, Wenwen Yu, Qiuwen Sun, Ruohan Zhao, Junfeng Hu
Formato: article
Lenguaje:EN
Publicado: IEEE 2021
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Acceso en línea:https://doaj.org/article/e246d9dba5aa49b89dd40c7392e666f7
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Sumario:With the widespread success of deep learning in biomedical image segmentation, domain shift becomes a critical and challenging problem, as the gap between two domains can severely affect model performance when deployed to unseen data with heterogeneous features. To alleviate this problem, we present a novel unsupervised domain adaptation network, for generalizing models learned from the labeled source domain to the unlabeled target domain for cross-modality biomedical image segmentation. Specifically, our approach consists of two key modules, a conditional domain discriminator (CDD) and a category-centric prototype aligner (CCPA). The CDD, extended from conditional domain adversarial networks in classifier tasks, is effective and robust in handling complex cross-modality biomedical images. The CCPA, improved from the graph-induced prototype alignment mechanism in cross-domain object detection, can exploit precise instance-level features through an elaborate prototype representation. In addition, it can address the negative effect of class imbalance via entropy-based loss. Extensive experiments on a public benchmark for the cardiac substructure segmentation task demonstrate that our method significantly improves performance on the target domain.