LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY

Subpopulation indices of peripheral blood and pleural exudate lymphocytes have been studied in the patients with various clinical variants of a tuberculous pleurisy. It has been shown that, in patients with both MBT-negative and MBT-positive variants of tubercular pleurisy, decreased quantity of CD3...

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Autores principales:	E. A. Jureva, O. V. Voronkova, O. I. Urazova, V. V. Novitsky, E. V. Nekrasov, I. O. Naslednikova, I. V. Maltseva, E. A. Peleganchuk, N. P. Pirogova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	tuberculous pleuritis lymphocytes lymphocyte subsets blood pleural exudate Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/e24ee326a3114b6391a0319a9745c6a2
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spelling	oai:doaj.org-article:e24ee326a3114b6391a0319a9745c6a22021-11-18T08:03:38ZLYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY1563-06252313-741X10.15789/1563-0625-2010-4-5-325-330https://doaj.org/article/e24ee326a3114b6391a0319a9745c6a22014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/140https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XSubpopulation indices of peripheral blood and pleural exudate lymphocytes have been studied in the patients with various clinical variants of a tuberculous pleurisy. It has been shown that, in patients with both MBT-negative and MBT-positive variants of tubercular pleurisy, decreased quantity of CD3- and CD4-positive lymphocytes was observed, whereas an increase in numbers of CD8+ and CD16+ lymphocytes was more pronounced in the persons with MBT-negative pleurisy. In pleural exudates from the patients with tubercular pleurisy, the numbers of CD3+ lymphocytes proved to be significantly higher than their contents in peripheral blood. It may be assumed that lymphocytosis in pleural exudates results from migration of the cells from peripheral blood into pleural cavity. It is revealed that, during exudative pleurisy of tuberculosis origin, T-cells with CD4+ and CD8+ phenotype are more likely subject to migration into pleural cavity, accomplished by additional migration of CD16+ lymphocytes in MBT-positive cases of pleurisy.E. A. JurevaO. V. VoronkovaO. I. UrazovaV. V. NovitskyE. V. NekrasovI. O. NaslednikovaI. V. MaltsevaE. A. PeleganchukN. P. PirogovaSPb RAACIarticletuberculous pleuritislymphocyteslymphocyte subsetsbloodpleural exudateImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 4-5, Pp 325-330 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	tuberculous pleuritis lymphocytes lymphocyte subsets blood pleural exudate Immunologic diseases. Allergy RC581-607
spellingShingle	tuberculous pleuritis lymphocytes lymphocyte subsets blood pleural exudate Immunologic diseases. Allergy RC581-607 E. A. Jureva O. V. Voronkova O. I. Urazova V. V. Novitsky E. V. Nekrasov I. O. Naslednikova I. V. Maltseva E. A. Peleganchuk N. P. Pirogova LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY
description	Subpopulation indices of peripheral blood and pleural exudate lymphocytes have been studied in the patients with various clinical variants of a tuberculous pleurisy. It has been shown that, in patients with both MBT-negative and MBT-positive variants of tubercular pleurisy, decreased quantity of CD3- and CD4-positive lymphocytes was observed, whereas an increase in numbers of CD8+ and CD16+ lymphocytes was more pronounced in the persons with MBT-negative pleurisy. In pleural exudates from the patients with tubercular pleurisy, the numbers of CD3+ lymphocytes proved to be significantly higher than their contents in peripheral blood. It may be assumed that lymphocytosis in pleural exudates results from migration of the cells from peripheral blood into pleural cavity. It is revealed that, during exudative pleurisy of tuberculosis origin, T-cells with CD4+ and CD8+ phenotype are more likely subject to migration into pleural cavity, accomplished by additional migration of CD16+ lymphocytes in MBT-positive cases of pleurisy.
format	article
author	E. A. Jureva O. V. Voronkova O. I. Urazova V. V. Novitsky E. V. Nekrasov I. O. Naslednikova I. V. Maltseva E. A. Peleganchuk N. P. Pirogova
author_facet	E. A. Jureva O. V. Voronkova O. I. Urazova V. V. Novitsky E. V. Nekrasov I. O. Naslednikova I. V. Maltseva E. A. Peleganchuk N. P. Pirogova
author_sort	E. A. Jureva
title	LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY
title_short	LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY
title_full	LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY
title_fullStr	LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY
title_full_unstemmed	LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY
title_sort	lymphocyte subpopulations of blood and pleural exudate in mbt-negative and mbt-positive tuberculous pleurisy
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/e24ee326a3114b6391a0319a9745c6a2
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LYMPHOCYTE SUBPOPULATIONS OF BLOOD AND PLEURAL EXUDATE IN MBT-NEGATIVE AND MBT-POSITIVE TUBERCULOUS PLEURISY

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