Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms

Deep brain stimulation (DBS) is a symptomatic treatment of Parkinson’s disease (PD) that benefits only a minority of patients. Here, the authors show that activation of cortical somatostatin interneurons alleviates motor symptoms in a mouse model of PD and may constitute a less invasive alternative...

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Bibliographic Details
Main Authors: Sébastien Valverde, Marie Vandecasteele, Charlotte Piette, Willy Derousseaux, Giuseppe Gangarossa, Asier Aristieta Arbelaiz, Jonathan Touboul, Bertrand Degos, Laurent Venance
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/e24ff63da61d4a89a39adb5c41f76a14
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