Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

ABSTRACT Efficient vaccination against infectious agents and tumors depends on specific antigen targeting to dendritic cells (DCs). We report here that biosafe coronavirus-based vaccine vectors facilitate delivery of multiple antigens and immunostimulatory cytokines to professional antigen-presentin...

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Autores principales: Luisa Cervantes-Barragan, Roland Züst, Reinhard Maier, Sophie Sierro, Jozef Janda, Frederic Levy, Daniel Speiser, Pedro Romero, Pierre-Simon Rohrlich, Burkhard Ludewig, Volker Thiel
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2010
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/e25819499c9c49ca9527573fd48a887c
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