Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients

Marwa Yahia Mahgoub,1 Ahmed Taha Abou Ghanima,1 Mohamed Nagy Elmohamady,2 Shaza Abdul Basset1 1Department of Rheumatology, Rehabilitation and Physical Medicine, Faculty of Medicine, Benha University, Benha, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Benha University, Benha, EgyptCorre...

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Autores principales:	Mahgoub MY, Abou Ghanima AT, Elmohamady MN, Abdul Basset S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	primary osteoarthritis age-related macular degeneration age-related diseases. Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/e258ed113a6144cc84530ae7a9c63ec1
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spelling	oai:doaj.org-article:e258ed113a6144cc84530ae7a9c63ec12021-12-02T09:08:29ZAge-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients1179-156Xhttps://doaj.org/article/e258ed113a6144cc84530ae7a9c63ec12020-03-01T00:00:00Zhttps://www.dovepress.com/age-related-macular-degeneration-in-primary-osteoarthritis-egyptian-pa-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XMarwa Yahia Mahgoub,1 Ahmed Taha Abou Ghanima,1 Mohamed Nagy Elmohamady,2 Shaza Abdul Basset1 1Department of Rheumatology, Rehabilitation and Physical Medicine, Faculty of Medicine, Benha University, Benha, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Benha University, Benha, EgyptCorrespondence: Marwa Yahia MahgoubDepartment of Rheumatology, Rehabilitation and Physical Medicine, Faculty of Medicine, Benha University, Benha, EgyptTel +20 1005530882Email marwa.yahia@fmed.bu.edu.egIntroduction: Both primary osteoarthritis (OA) and age-related macular degeneration (AMD) cause disability in old people. This study aimed to detect the relation between primary osteoarthritis and age-related macular degeneration in a sample of geriatric Egyptian population.Methods: This cross-sectional study included 222 primary OA patients. Medical history, musculoskeletal examination, body mass index (BMI) calculation, and ophthalmological examination, radiographs of anteroposterior view and weight-bearing position for both hips and both knees and posteroanterior view for hands, Kellgren and Lawrence grading score for radiological severity of OA, optical coherence tomography (OCT), and fundus fluorescence angiography FFA for evaluation of the macula were done. AMD was classified into early, intermediate, and late. The collected data were analyzed using SPSS version 25.0.Results: Forty-six OA patients had AMD [19 cases had early, 15 cases had intermediate and 12 cases with late (7 neovascular (NV) and 5 geographic atrophy (GA))]. There was a significant correlation between AMD stages and OA grading score. There were significant differences between OA patient with AMD and those without AMD regarding age, disease duration, disease severity, family history of OA, daily mild exercise and calcium, and vitamin D intake. Multivariable analysis revealed that older age, more severe OA, low exercise and less calcium and vitamin D intake were considered independent risk factors for AMD development in primary OA.Conclusion: Primary OA patients are more liable to AMD due to common risk factors and related pathogenesis. Ophthalmological follow up of those patients is recommended.Keywords: primary osteoarthritis, age-related macular degeneration, age-related diseasesMahgoub MYAbou Ghanima ATElmohamady MNAbdul Basset SDove Medical Pressarticleprimary osteoarthritisage-related macular degenerationage-related diseases.Diseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 12, Pp 35-40 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	primary osteoarthritis age-related macular degeneration age-related diseases. Diseases of the musculoskeletal system RC925-935
spellingShingle	primary osteoarthritis age-related macular degeneration age-related diseases. Diseases of the musculoskeletal system RC925-935 Mahgoub MY Abou Ghanima AT Elmohamady MN Abdul Basset S Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients
description	Marwa Yahia Mahgoub,1 Ahmed Taha Abou Ghanima,1 Mohamed Nagy Elmohamady,2 Shaza Abdul Basset1 1Department of Rheumatology, Rehabilitation and Physical Medicine, Faculty of Medicine, Benha University, Benha, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Benha University, Benha, EgyptCorrespondence: Marwa Yahia MahgoubDepartment of Rheumatology, Rehabilitation and Physical Medicine, Faculty of Medicine, Benha University, Benha, EgyptTel +20 1005530882Email marwa.yahia@fmed.bu.edu.egIntroduction: Both primary osteoarthritis (OA) and age-related macular degeneration (AMD) cause disability in old people. This study aimed to detect the relation between primary osteoarthritis and age-related macular degeneration in a sample of geriatric Egyptian population.Methods: This cross-sectional study included 222 primary OA patients. Medical history, musculoskeletal examination, body mass index (BMI) calculation, and ophthalmological examination, radiographs of anteroposterior view and weight-bearing position for both hips and both knees and posteroanterior view for hands, Kellgren and Lawrence grading score for radiological severity of OA, optical coherence tomography (OCT), and fundus fluorescence angiography FFA for evaluation of the macula were done. AMD was classified into early, intermediate, and late. The collected data were analyzed using SPSS version 25.0.Results: Forty-six OA patients had AMD [19 cases had early, 15 cases had intermediate and 12 cases with late (7 neovascular (NV) and 5 geographic atrophy (GA))]. There was a significant correlation between AMD stages and OA grading score. There were significant differences between OA patient with AMD and those without AMD regarding age, disease duration, disease severity, family history of OA, daily mild exercise and calcium, and vitamin D intake. Multivariable analysis revealed that older age, more severe OA, low exercise and less calcium and vitamin D intake were considered independent risk factors for AMD development in primary OA.Conclusion: Primary OA patients are more liable to AMD due to common risk factors and related pathogenesis. Ophthalmological follow up of those patients is recommended.Keywords: primary osteoarthritis, age-related macular degeneration, age-related diseases
format	article
author	Mahgoub MY Abou Ghanima AT Elmohamady MN Abdul Basset S
author_facet	Mahgoub MY Abou Ghanima AT Elmohamady MN Abdul Basset S
author_sort	Mahgoub MY
title	Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients
title_short	Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients
title_full	Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients
title_fullStr	Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients
title_full_unstemmed	Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients
title_sort	age-related macular degeneration in primary osteoarthritis egyptian patients
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/e258ed113a6144cc84530ae7a9c63ec1
work_keys_str_mv	AT mahgoubmy agerelatedmaculardegenerationinprimaryosteoarthritisegyptianpatients AT aboughanimaat agerelatedmaculardegenerationinprimaryosteoarthritisegyptianpatients AT elmohamadymn agerelatedmaculardegenerationinprimaryosteoarthritisegyptianpatients AT abdulbassets agerelatedmaculardegenerationinprimaryosteoarthritisegyptianpatients
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Age-Related Macular Degeneration in Primary Osteoarthritis Egyptian Patients

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