A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.

Resveratrol in high doses has been shown to extend lifespan in some studies in invertebrates and to prevent early mortality in mice fed a high-fat diet. We fed mice from middle age (14-months) to old age (30-months) either a control diet, a low dose of resveratrol (4.9 mg kg(-1) day(-1)), or a calor...

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Auteurs principaux: Jamie L Barger, Tsuyoshi Kayo, James M Vann, Edward B Arias, Jelai Wang, Timothy A Hacker, Ying Wang, Daniel Raederstorff, Jason D Morrow, Christiaan Leeuwenburgh, David B Allison, Kurt W Saupe, Gregory D Cartee, Richard Weindruch, Tomas A Prolla
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/e25f222114b3420ba995866183387c34
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https://doaj.org/article/e25f222114b3420ba995866183387c34

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