Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization

Electrical Impedance Tomography (EIT) is a clinically used tool for bed-side monitoring of ventilation. Previous work also showed a high potential for lung perfusion monitoring with indicator-enhanced EIT. However, many research questions have yet to be answered before it can be broadly applied in c...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Augustin Xenia, Kircher Michael, Dössel Olaf, Stender Birgit, Bluth Thomas, Gama de Abreu Marcelo
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2020
Materias:
eit
rbf
R
Acceso en línea:https://doaj.org/article/e270a61a01434ef8ac0fde6a8dc8ab7d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:e270a61a01434ef8ac0fde6a8dc8ab7d
record_format dspace
spelling oai:doaj.org-article:e270a61a01434ef8ac0fde6a8dc8ab7d2021-12-05T14:10:42ZEstimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization2364-550410.1515/cdbme-2020-3016https://doaj.org/article/e270a61a01434ef8ac0fde6a8dc8ab7d2020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3016https://doaj.org/toc/2364-5504Electrical Impedance Tomography (EIT) is a clinically used tool for bed-side monitoring of ventilation. Previous work also showed a high potential for lung perfusion monitoring with indicator-enhanced EIT. However, many research questions have yet to be answered before it can be broadly applied in clinical everyday life. The goal of this work is to evaluate a new method to improve EIT perfusion measurements. Pulmonary hemodynamic transfer functions were estimated using regularized deconvolution with Tikhonov regularization to estimate spatial perfusion parameters. The final comparison between EIT images and PET scans showed a median correlation of 0.897 for the images which were reconstructed using the regularized deconvolution. In comparison the previously used maximum slope method led to a median correlation of 0.868.Augustin XeniaKircher MichaelDössel OlafStender BirgitBluth ThomasGama de Abreu MarceloDe Gruyterarticleeitperfusion measurementrbftikhonov regularizationmaximum slopeimage reconstructionMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 60-63 (2020)
institution DOAJ
collection DOAJ
language EN
topic eit
perfusion measurement
rbf
tikhonov regularization
maximum slope
image reconstruction
Medicine
R
spellingShingle eit
perfusion measurement
rbf
tikhonov regularization
maximum slope
image reconstruction
Medicine
R
Augustin Xenia
Kircher Michael
Dössel Olaf
Stender Birgit
Bluth Thomas
Gama de Abreu Marcelo
Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
description Electrical Impedance Tomography (EIT) is a clinically used tool for bed-side monitoring of ventilation. Previous work also showed a high potential for lung perfusion monitoring with indicator-enhanced EIT. However, many research questions have yet to be answered before it can be broadly applied in clinical everyday life. The goal of this work is to evaluate a new method to improve EIT perfusion measurements. Pulmonary hemodynamic transfer functions were estimated using regularized deconvolution with Tikhonov regularization to estimate spatial perfusion parameters. The final comparison between EIT images and PET scans showed a median correlation of 0.897 for the images which were reconstructed using the regularized deconvolution. In comparison the previously used maximum slope method led to a median correlation of 0.868.
format article
author Augustin Xenia
Kircher Michael
Dössel Olaf
Stender Birgit
Bluth Thomas
Gama de Abreu Marcelo
author_facet Augustin Xenia
Kircher Michael
Dössel Olaf
Stender Birgit
Bluth Thomas
Gama de Abreu Marcelo
author_sort Augustin Xenia
title Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
title_short Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
title_full Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
title_fullStr Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
title_full_unstemmed Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
title_sort estimating regional pulmonary blood flow in eit with regularized deconvolution with a tikhonov regularization
publisher De Gruyter
publishDate 2020
url https://doaj.org/article/e270a61a01434ef8ac0fde6a8dc8ab7d
work_keys_str_mv AT augustinxenia estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization
AT kirchermichael estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization
AT dosselolaf estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization
AT stenderbirgit estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization
AT bluththomas estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization
AT gamadeabreumarcelo estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization
_version_ 1718371813439832064