Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization
Electrical Impedance Tomography (EIT) is a clinically used tool for bed-side monitoring of ventilation. Previous work also showed a high potential for lung perfusion monitoring with indicator-enhanced EIT. However, many research questions have yet to be answered before it can be broadly applied in c...
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2020
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oai:doaj.org-article:e270a61a01434ef8ac0fde6a8dc8ab7d2021-12-05T14:10:42ZEstimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization2364-550410.1515/cdbme-2020-3016https://doaj.org/article/e270a61a01434ef8ac0fde6a8dc8ab7d2020-09-01T00:00:00Zhttps://doi.org/10.1515/cdbme-2020-3016https://doaj.org/toc/2364-5504Electrical Impedance Tomography (EIT) is a clinically used tool for bed-side monitoring of ventilation. Previous work also showed a high potential for lung perfusion monitoring with indicator-enhanced EIT. However, many research questions have yet to be answered before it can be broadly applied in clinical everyday life. The goal of this work is to evaluate a new method to improve EIT perfusion measurements. Pulmonary hemodynamic transfer functions were estimated using regularized deconvolution with Tikhonov regularization to estimate spatial perfusion parameters. The final comparison between EIT images and PET scans showed a median correlation of 0.897 for the images which were reconstructed using the regularized deconvolution. In comparison the previously used maximum slope method led to a median correlation of 0.868.Augustin XeniaKircher MichaelDössel OlafStender BirgitBluth ThomasGama de Abreu MarceloDe Gruyterarticleeitperfusion measurementrbftikhonov regularizationmaximum slopeimage reconstructionMedicineRENCurrent Directions in Biomedical Engineering, Vol 6, Iss 3, Pp 60-63 (2020) |
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eit perfusion measurement rbf tikhonov regularization maximum slope image reconstruction Medicine R |
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eit perfusion measurement rbf tikhonov regularization maximum slope image reconstruction Medicine R Augustin Xenia Kircher Michael Dössel Olaf Stender Birgit Bluth Thomas Gama de Abreu Marcelo Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization |
description |
Electrical Impedance Tomography (EIT) is a clinically used tool for bed-side monitoring of ventilation. Previous work also showed a high potential for lung perfusion monitoring with indicator-enhanced EIT. However, many research questions have yet to be answered before it can be broadly applied in clinical everyday life. The goal of this work is to evaluate a new method to improve EIT perfusion measurements. Pulmonary hemodynamic transfer functions were estimated using regularized deconvolution with Tikhonov regularization to estimate spatial perfusion parameters. The final comparison between EIT images and PET scans showed a median correlation of 0.897 for the images which were reconstructed using the regularized deconvolution. In comparison the previously used maximum slope method led to a median correlation of 0.868. |
format |
article |
author |
Augustin Xenia Kircher Michael Dössel Olaf Stender Birgit Bluth Thomas Gama de Abreu Marcelo |
author_facet |
Augustin Xenia Kircher Michael Dössel Olaf Stender Birgit Bluth Thomas Gama de Abreu Marcelo |
author_sort |
Augustin Xenia |
title |
Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization |
title_short |
Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization |
title_full |
Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization |
title_fullStr |
Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization |
title_full_unstemmed |
Estimating regional pulmonary blood flow in EIT with regularized deconvolution with a Tikhonov regularization |
title_sort |
estimating regional pulmonary blood flow in eit with regularized deconvolution with a tikhonov regularization |
publisher |
De Gruyter |
publishDate |
2020 |
url |
https://doaj.org/article/e270a61a01434ef8ac0fde6a8dc8ab7d |
work_keys_str_mv |
AT augustinxenia estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization AT kirchermichael estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization AT dosselolaf estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization AT stenderbirgit estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization AT bluththomas estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization AT gamadeabreumarcelo estimatingregionalpulmonarybloodflowineitwithregularizeddeconvolutionwithatikhonovregularization |
_version_ |
1718371813439832064 |