Association of depressive disorder with biochemical and anthropometric indices in adult men and women

Abstract Depression is a common psychiatric disorder. Although many risk factors for depression have been reported, the associations of biochemical and anthropometric indices with depressive disorder remain unclear. The objective of this study was to assess whether there are significant associations...

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Autor principal: Bum Ju Lee
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Publicado: Nature Portfolio 2021
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spelling oai:doaj.org-article:e274d9434bdf4ff792b112ec046e891f2021-12-02T16:10:27ZAssociation of depressive disorder with biochemical and anthropometric indices in adult men and women10.1038/s41598-021-93103-02045-2322https://doaj.org/article/e274d9434bdf4ff792b112ec046e891f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93103-0https://doaj.org/toc/2045-2322Abstract Depression is a common psychiatric disorder. Although many risk factors for depression have been reported, the associations of biochemical and anthropometric indices with depressive disorder remain unclear. The objective of this study was to assess whether there are significant associations of depressive disorder with biochemical and obesity indices. This study was based on data from the Korea National Health and Nutrition Examination Survey from 2007 to 2018, and logistic regression was performed to examine the association of depression with biochemical and obesity indices. A total of 33,993 subjects were included in the analyses. Study subjects consisted of 13,178 men in the control group (mean age of 51.12 years), 509 men in the depression group (53.67), 18,279 women in the control group (50.5), and 2027 women in the depression group (55.39). Among men, the depression group was significantly more likely to have a lower height and weight than the control group. Compared to the control group, the depression group was more likely to have higher triglyceride levels and tended to have lower hematocrit and blood urea nitrogen (BUN) levels. Among women, the depression group was more likely to have higher triglyceride, aspartate aminotransferase (AST), BUN, and creatinine levels and lower high-density lipoprotein cholesterol (HDL-C), hematocrit, and red blood cell counts. Several biochemical and anthropometric indices used in this study were associated with depressive disorder, but these associations may differ according to sex.Bum Ju LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Bum Ju Lee
Association of depressive disorder with biochemical and anthropometric indices in adult men and women
description Abstract Depression is a common psychiatric disorder. Although many risk factors for depression have been reported, the associations of biochemical and anthropometric indices with depressive disorder remain unclear. The objective of this study was to assess whether there are significant associations of depressive disorder with biochemical and obesity indices. This study was based on data from the Korea National Health and Nutrition Examination Survey from 2007 to 2018, and logistic regression was performed to examine the association of depression with biochemical and obesity indices. A total of 33,993 subjects were included in the analyses. Study subjects consisted of 13,178 men in the control group (mean age of 51.12 years), 509 men in the depression group (53.67), 18,279 women in the control group (50.5), and 2027 women in the depression group (55.39). Among men, the depression group was significantly more likely to have a lower height and weight than the control group. Compared to the control group, the depression group was more likely to have higher triglyceride levels and tended to have lower hematocrit and blood urea nitrogen (BUN) levels. Among women, the depression group was more likely to have higher triglyceride, aspartate aminotransferase (AST), BUN, and creatinine levels and lower high-density lipoprotein cholesterol (HDL-C), hematocrit, and red blood cell counts. Several biochemical and anthropometric indices used in this study were associated with depressive disorder, but these associations may differ according to sex.
format article
author Bum Ju Lee
author_facet Bum Ju Lee
author_sort Bum Ju Lee
title Association of depressive disorder with biochemical and anthropometric indices in adult men and women
title_short Association of depressive disorder with biochemical and anthropometric indices in adult men and women
title_full Association of depressive disorder with biochemical and anthropometric indices in adult men and women
title_fullStr Association of depressive disorder with biochemical and anthropometric indices in adult men and women
title_full_unstemmed Association of depressive disorder with biochemical and anthropometric indices in adult men and women
title_sort association of depressive disorder with biochemical and anthropometric indices in adult men and women
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e274d9434bdf4ff792b112ec046e891f
work_keys_str_mv AT bumjulee associationofdepressivedisorderwithbiochemicalandanthropometricindicesinadultmenandwomen
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