Pathophysiology of diabetes: An overview

Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both. Hyperglycemia manifests in various forms with a va...

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Autores principales:	Mujeeb Z Banday, Aga S Sameer, Saniya Nissar
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Materias:	diabetes mellitus endocrinopathies gestational diabetes maturity-onset diabetes of the young neonatal diabetes Medicine R
Acceso en línea:	https://doaj.org/article/e277c51b4f7d46c48edfd0b23c1f62e3
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spelling	oai:doaj.org-article:e277c51b4f7d46c48edfd0b23c1f62e32021-12-02T17:00:58ZPathophysiology of diabetes: An overview2231-07702249-446410.4103/ajm.ajm_53_20https://doaj.org/article/e277c51b4f7d46c48edfd0b23c1f62e32020-10-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.ajm_53_20https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both. Hyperglycemia manifests in various forms with a varied presentation and results in carbohydrate, fat, and protein metabolic dysfunctions. Long-term hyperglycemia often leads to various microvascular and macrovascular diabetic complications, which are mainly responsible for diabetes-associated morbidity and mortality. Hyperglycemia serves as the primary biomarker for the diagnosis of diabetes as well. In this review, we would be focusing on the classification of diabetes and its pathophysiology including that of its various types.Mujeeb Z BandayAga S SameerSaniya NissarThieme Medical and Scientific Publishers Pvt. Ltd.articlediabetes mellitusendocrinopathiesgestational diabetesmaturity-onset diabetes of the youngneonatal diabetesMedicineRENAvicenna Journal of Medicine, Vol 10, Iss 04, Pp 174-188 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes mellitus endocrinopathies gestational diabetes maturity-onset diabetes of the young neonatal diabetes Medicine R
spellingShingle	diabetes mellitus endocrinopathies gestational diabetes maturity-onset diabetes of the young neonatal diabetes Medicine R Mujeeb Z Banday Aga S Sameer Saniya Nissar Pathophysiology of diabetes: An overview
description	Diabetes mellitus is a chronic heterogeneous metabolic disorder with complex pathogenesis. It is characterized by elevated blood glucose levels or hyperglycemia, which results from abnormalities in either insulin secretion or insulin action or both. Hyperglycemia manifests in various forms with a varied presentation and results in carbohydrate, fat, and protein metabolic dysfunctions. Long-term hyperglycemia often leads to various microvascular and macrovascular diabetic complications, which are mainly responsible for diabetes-associated morbidity and mortality. Hyperglycemia serves as the primary biomarker for the diagnosis of diabetes as well. In this review, we would be focusing on the classification of diabetes and its pathophysiology including that of its various types.
format	article
author	Mujeeb Z Banday Aga S Sameer Saniya Nissar
author_facet	Mujeeb Z Banday Aga S Sameer Saniya Nissar
author_sort	Mujeeb Z Banday
title	Pathophysiology of diabetes: An overview
title_short	Pathophysiology of diabetes: An overview
title_full	Pathophysiology of diabetes: An overview
title_fullStr	Pathophysiology of diabetes: An overview
title_full_unstemmed	Pathophysiology of diabetes: An overview
title_sort	pathophysiology of diabetes: an overview
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2020
url	https://doaj.org/article/e277c51b4f7d46c48edfd0b23c1f62e3
work_keys_str_mv	AT mujeebzbanday pathophysiologyofdiabetesanoverview AT agassameer pathophysiologyofdiabetesanoverview AT saniyanissar pathophysiologyofdiabetesanoverview
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Pathophysiology of diabetes: An overview

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