Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea

Qingzhuan tea (QZT) is a typical Chinese dark tea that has a long-time manufacturing process. In the present study, liquid chromatography coupled with tandem mass spectrometry was used to study the chemical changes of tea samples during QZT processing. Untargeted metabolomics analysis revealed that...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Peng-Cheng Zheng, Chun-Yin Qin, Pan-Pan Liu, Lin Feng, Tie-Jun Ling, Jing-Ming Ning, Liang Zhang, Xiao-Chun Wan
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	qingzhuan tea metabolomics pile-fermentation sensory evaluation bioactivities Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/e279119dd110413fab4707fed6f2424d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e279119dd110413fab4707fed6f2424d
record_format	dspace
spelling	oai:doaj.org-article:e279119dd110413fab4707fed6f2424d2021-11-11T18:39:36ZUntargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea10.3390/molecules262167181420-3049https://doaj.org/article/e279119dd110413fab4707fed6f2424d2021-11-01T00:00:00Zhttps://www.mdpi.com/1420-3049/26/21/6718https://doaj.org/toc/1420-3049Qingzhuan tea (QZT) is a typical Chinese dark tea that has a long-time manufacturing process. In the present study, liquid chromatography coupled with tandem mass spectrometry was used to study the chemical changes of tea samples during QZT processing. Untargeted metabolomics analysis revealed that the pile-fermentation and turnover (post-fermentation, FT) was the crucial stage in transforming the main compounds of QZT, whose contents of flavan-3-ols and flavonoids glycosides were decreased significantly. The bioactivities, including the antioxidant capacities and inhibitory effects on α-amylase and α-glucosidase, were also reduced after the FT process. It was suggested that although the QZT sensory properties improved following pile-fermentation and aging, the bioactivities remained restrained. Correlation analysis indicated that the main galloylated catechins and flavonoid glycosides were highly related to their antioxidant capacity and inhibitory effects on α-amylase and α-glucosidase.Peng-Cheng ZhengChun-Yin QinPan-Pan LiuLin FengTie-Jun LingJing-Ming NingLiang ZhangXiao-Chun WanMDPI AGarticleqingzhuan teametabolomicspile-fermentationsensory evaluationbioactivitiesOrganic chemistryQD241-441ENMolecules, Vol 26, Iss 6718, p 6718 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	qingzhuan tea metabolomics pile-fermentation sensory evaluation bioactivities Organic chemistry QD241-441
spellingShingle	qingzhuan tea metabolomics pile-fermentation sensory evaluation bioactivities Organic chemistry QD241-441 Peng-Cheng Zheng Chun-Yin Qin Pan-Pan Liu Lin Feng Tie-Jun Ling Jing-Ming Ning Liang Zhang Xiao-Chun Wan Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea
description	Qingzhuan tea (QZT) is a typical Chinese dark tea that has a long-time manufacturing process. In the present study, liquid chromatography coupled with tandem mass spectrometry was used to study the chemical changes of tea samples during QZT processing. Untargeted metabolomics analysis revealed that the pile-fermentation and turnover (post-fermentation, FT) was the crucial stage in transforming the main compounds of QZT, whose contents of flavan-3-ols and flavonoids glycosides were decreased significantly. The bioactivities, including the antioxidant capacities and inhibitory effects on α-amylase and α-glucosidase, were also reduced after the FT process. It was suggested that although the QZT sensory properties improved following pile-fermentation and aging, the bioactivities remained restrained. Correlation analysis indicated that the main galloylated catechins and flavonoid glycosides were highly related to their antioxidant capacity and inhibitory effects on α-amylase and α-glucosidase.
format	article
author	Peng-Cheng Zheng Chun-Yin Qin Pan-Pan Liu Lin Feng Tie-Jun Ling Jing-Ming Ning Liang Zhang Xiao-Chun Wan
author_facet	Peng-Cheng Zheng Chun-Yin Qin Pan-Pan Liu Lin Feng Tie-Jun Ling Jing-Ming Ning Liang Zhang Xiao-Chun Wan
author_sort	Peng-Cheng Zheng
title	Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea
title_short	Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea
title_full	Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea
title_fullStr	Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea
title_full_unstemmed	Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea
title_sort	untargeted metabolomics combined with bioassay reveals the change in critical bioactive compounds during the processing of qingzhuan tea
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/e279119dd110413fab4707fed6f2424d
work_keys_str_mv	AT pengchengzheng untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT chunyinqin untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT panpanliu untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT linfeng untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT tiejunling untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT jingmingning untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT liangzhang untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea AT xiaochunwan untargetedmetabolomicscombinedwithbioassayrevealsthechangeincriticalbioactivecompoundsduringtheprocessingofqingzhuantea
_version_	1718431793618616320

Untargeted Metabolomics Combined with Bioassay Reveals the Change in Critical Bioactive Compounds during the Processing of Qingzhuan Tea

Ejemplares similares