Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
Introduction: Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) is a common health problem coupled with huge mortality and morbidity across the world. Acute exacerbation in COPD patients leads to electrolyte disturbances. Routinely, electrolytes are measured from venous blood....
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
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JCDR Research and Publications Private Limited
2021
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| Acceso en línea: | https://doaj.org/article/e27ec9d705ee4d8aac377df8a2fc3334 |
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| Sumario: | Introduction: Acute Exacerbation of Chronic Obstructive Pulmonary
Disease (AECOPD) is a common health problem coupled with
huge mortality and morbidity across the world. Acute exacerbation
in COPD patients leads to electrolyte disturbances. Routinely,
electrolytes are measured from venous blood. Electrolytes can also
be measured from whole blood by blood gas analyser along with
blood gases measurement.
Aim: To study the correlation between venous and arterial blood
electrolytes in AECOPD patients.
Materials and Methods: The cross-sectional study was conducted
at Clinical Biochemistry Laboratory, Government Medical College
and Sir Takhtsinhji General Hospital, Bhavnagar, Gujarat, India,
from December 2013 to May 2014. Arterial and venous blood were
taken at same time from 150 patients of AECOPD and analysed
for electrolytes (sodium, potassium and ionised calcium) in arterial
blood gas analyser. Correlation of arterial and venous blood
electrolyte levels was done by Pearson’s correlation.
Results: This study comprised 109 (72.67%) male and 41 (27.33%)
female AECOPD patients. Mean age of subjects was 59.01±11.42
years. Mean level of arterial sodium was 143.1±8.81 mmol/L and
venous sodium was 144.8±8.47 mmol/L (p-value=0.0973). Mean
level of arterial potassium was 3.53±0.73 mmol/L and venous
potassium was 3.19±0.56 mmol/L (p-value <0.0001). Mean level of
arterial ionised calcium was 0.83±0.13 mmol/L and venous ionised
calcium was 0.76±0.17 mmol/L (p-value <0.0001). Correlation
coefficient values for sodium, potassium and ionised calcium were
0.878, 0.762 and 0.537, respectively.
Conclusion: Arterial sodium and potassium can be used as a
substitute of venous sodium and potassium in management of
AECOPD patients, while arterial ionised calcium should not be used
in place of venous ionised calcium in management of such patients. |
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