Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study

Introduction: Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) is a common health problem coupled with huge mortality and morbidity across the world. Acute exacerbation in COPD patients leads to electrolyte disturbances. Routinely, electrolytes are measured from venous blood....

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Autores principales: Amitkumar Virji Maheshwari, Hardik N Javia, Hariom Sharma, Bhavesh Ramji Sadariya
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Publicado: JCDR Research and Publications Private Limited 2021
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Acceso en línea:https://doaj.org/article/e27ec9d705ee4d8aac377df8a2fc3334
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spelling oai:doaj.org-article:e27ec9d705ee4d8aac377df8a2fc33342021-11-07T07:13:29ZCorrelation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study10.7860/JCDR/2021/50336.154022249-782X0973-709Xhttps://doaj.org/article/e27ec9d705ee4d8aac377df8a2fc33342021-09-01T00:00:00Zhttps://www.jcdr.net/articles/PDF/15402/50336_CE[Ra1]_F[SH]_PF1(SC_RK)_PFA(SC_KM)_PN(KM).pdfhttps://doaj.org/toc/2249-782Xhttps://doaj.org/toc/0973-709XIntroduction: Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) is a common health problem coupled with huge mortality and morbidity across the world. Acute exacerbation in COPD patients leads to electrolyte disturbances. Routinely, electrolytes are measured from venous blood. Electrolytes can also be measured from whole blood by blood gas analyser along with blood gases measurement. Aim: To study the correlation between venous and arterial blood electrolytes in AECOPD patients. Materials and Methods: The cross-sectional study was conducted at Clinical Biochemistry Laboratory, Government Medical College and Sir Takhtsinhji General Hospital, Bhavnagar, Gujarat, India, from December 2013 to May 2014. Arterial and venous blood were taken at same time from 150 patients of AECOPD and analysed for electrolytes (sodium, potassium and ionised calcium) in arterial blood gas analyser. Correlation of arterial and venous blood electrolyte levels was done by Pearson’s correlation. Results: This study comprised 109 (72.67%) male and 41 (27.33%) female AECOPD patients. Mean age of subjects was 59.01±11.42 years. Mean level of arterial sodium was 143.1±8.81 mmol/L and venous sodium was 144.8±8.47 mmol/L (p-value=0.0973). Mean level of arterial potassium was 3.53±0.73 mmol/L and venous potassium was 3.19±0.56 mmol/L (p-value <0.0001). Mean level of arterial ionised calcium was 0.83±0.13 mmol/L and venous ionised calcium was 0.76±0.17 mmol/L (p-value <0.0001). Correlation coefficient values for sodium, potassium and ionised calcium were 0.878, 0.762 and 0.537, respectively. Conclusion: Arterial sodium and potassium can be used as a substitute of venous sodium and potassium in management of AECOPD patients, while arterial ionised calcium should not be used in place of venous ionised calcium in management of such patients.Amitkumar Virji MaheshwariHardik N JaviaHariom SharmaBhavesh Ramji SadariyaJCDR Research and Publications Private Limitedarticlearterial blood gas analyserion selective electrodeionised calciumpotassiumsodiumMedicineRENJournal of Clinical and Diagnostic Research, Vol 15, Iss 9, Pp BC14-BC17 (2021)
institution DOAJ
collection DOAJ
language EN
topic arterial blood gas analyser
ion selective electrode
ionised calcium
potassium
sodium
Medicine
R
spellingShingle arterial blood gas analyser
ion selective electrode
ionised calcium
potassium
sodium
Medicine
R
Amitkumar Virji Maheshwari
Hardik N Javia
Hariom Sharma
Bhavesh Ramji Sadariya
Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
description Introduction: Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) is a common health problem coupled with huge mortality and morbidity across the world. Acute exacerbation in COPD patients leads to electrolyte disturbances. Routinely, electrolytes are measured from venous blood. Electrolytes can also be measured from whole blood by blood gas analyser along with blood gases measurement. Aim: To study the correlation between venous and arterial blood electrolytes in AECOPD patients. Materials and Methods: The cross-sectional study was conducted at Clinical Biochemistry Laboratory, Government Medical College and Sir Takhtsinhji General Hospital, Bhavnagar, Gujarat, India, from December 2013 to May 2014. Arterial and venous blood were taken at same time from 150 patients of AECOPD and analysed for electrolytes (sodium, potassium and ionised calcium) in arterial blood gas analyser. Correlation of arterial and venous blood electrolyte levels was done by Pearson’s correlation. Results: This study comprised 109 (72.67%) male and 41 (27.33%) female AECOPD patients. Mean age of subjects was 59.01±11.42 years. Mean level of arterial sodium was 143.1±8.81 mmol/L and venous sodium was 144.8±8.47 mmol/L (p-value=0.0973). Mean level of arterial potassium was 3.53±0.73 mmol/L and venous potassium was 3.19±0.56 mmol/L (p-value <0.0001). Mean level of arterial ionised calcium was 0.83±0.13 mmol/L and venous ionised calcium was 0.76±0.17 mmol/L (p-value <0.0001). Correlation coefficient values for sodium, potassium and ionised calcium were 0.878, 0.762 and 0.537, respectively. Conclusion: Arterial sodium and potassium can be used as a substitute of venous sodium and potassium in management of AECOPD patients, while arterial ionised calcium should not be used in place of venous ionised calcium in management of such patients.
format article
author Amitkumar Virji Maheshwari
Hardik N Javia
Hariom Sharma
Bhavesh Ramji Sadariya
author_facet Amitkumar Virji Maheshwari
Hardik N Javia
Hariom Sharma
Bhavesh Ramji Sadariya
author_sort Amitkumar Virji Maheshwari
title Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
title_short Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
title_full Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
title_fullStr Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
title_full_unstemmed Correlation between Arterial and Venous Blood Electrolytes in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-sectional Study
title_sort correlation between arterial and venous blood electrolytes in acute exacerbation of chronic obstructive pulmonary disease: a cross-sectional study
publisher JCDR Research and Publications Private Limited
publishDate 2021
url https://doaj.org/article/e27ec9d705ee4d8aac377df8a2fc3334
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