LpxK Is Essential for Growth of <named-content content-type="genus-species">Acinetobacter baumannii</named-content> ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

LpxK Is Essential for Growth of <named-content content-type="genus-species">Acinetobacter baumannii</named-content> ATCC 19606: Relationship to Toxic Accumulation of Lipid A Pathway Intermediates

ABSTRACT Acinetobacter baumannii ATCC 19606 can grow without lipid A, the major component of lipooligosaccharide. However, we previously reported that depletion of LpxH (the fourth enzyme in the lipid A biosynthetic pathway) prevented growth of this strain due to toxic accumulation of lipid A pathwa...

Full description

Saved in:
Bibliographic Details
Main Authors: Jun-Rong Wei, Daryl L. Richie, Mina Mostafavi, Louis E. Metzger, Christopher M. Rath, William S. Sawyer, Kenneth T. Takeoka, Charles R. Dean
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Acinetobacter baumannii
LpxK
lipid A
outer membrane
Microbiology
QR1-502
Online Access:https://doaj.org/article/e288e2e6824e4e1d854b8e90cdc75dee
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/e288e2e6824e4e1d854b8e90cdc75dee

Similar Items