YAP1/TAZ drives ependymoma-like tumour formation in mice

YAP1/TAZ drives ependymoma-like tumour formation in mice

YAP1 gene fusions are found in subgroups of paediatric ependymomas. Here the authors show that YAP1 activation in NeuroD6 positive neuronal precursor cells can induce ependymoma-like tumours in mice.

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Detalles Bibliográficos
Autores principales: Noreen Eder, Federico Roncaroli, Marie-Charlotte Domart, Stuart Horswell, Felipe Andreiuolo, Helen R. Flynn, Andre T. Lopes, Suzanne Claxton, John-Paul Kilday, Lucy Collinson, Jun-Hao Mao, Torsten Pietsch, Barry Thompson, Ambrosius P. Snijders, Sila K. Ultanir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/e28a2ae9a5014ff08a75f121065097ec
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