Dimethyl Fumarate Ameliorates Nucleus Pulposus Cell Dysfunction through Activating the Nrf2/HO-1 Pathway in Intervertebral Disc Degeneration

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Dimethyl Fumarate Ameliorates Nucleus Pulposus Cell Dysfunction through Activating the Nrf2/HO-1 Pathway in Intervertebral Disc Degeneration

Background. Oxidative stress, inflammation, and nucleus pulposus cells (NPCs) apoptosis are involved in pathogenesis of intervertebral disc (IVD) degeneration (IVDD). Dimethyl fumarate (DMF) has been found to effectively depress oxidative stress and inflammation via the Nrf2 pathway. Hence, this pro...

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Détails bibliographiques
Auteurs principaux:	Ruihong Wang, Dawei Luo, Zhiwei Li, Huimin Han
Format:	article
Langue:	EN
Publié:	Hindawi Limited 2021
Sujets:	Computer applications to medicine. Medical informatics R858-859.7
Accès en ligne:	https://doaj.org/article/e28a3a5b108942fdb65b322dcb56380f
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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