A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties

The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has bee...

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Autores principales:	Łukasz Balewski, Sylwia Szulta, Aleksandra Jalińska, Anita Kornicka
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	coumarin 2H-chromen-2-one metal complexes biological activity fluorescent properties Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/e28b27cbd51a4be89cca7b0fbdc1c18d
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spelling	oai:doaj.org-article:e28b27cbd51a4be89cca7b0fbdc1c18d2021-12-01T23:04:45ZA Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties2296-264610.3389/fchem.2021.781779https://doaj.org/article/e28b27cbd51a4be89cca7b0fbdc1c18d2021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fchem.2021.781779/fullhttps://doaj.org/toc/2296-2646The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has been reported that the incorporation of a metal ion into coumarin derivatives can increase the activity of such complexes compared to coumarin-based ligands. Accordingly, some of them have been found to display promising antioxidant, antitumor or antibacterial activities. This mini-review briefly summarizes the recent development of coumarin-metal complexes with proven biological properties. The attention is also paid to agents for which practical applications in the detection of biologically important species may be found.Łukasz BalewskiSylwia SzultaAleksandra JalińskaAnita KornickaFrontiers Media S.A.articlecoumarin2H-chromen-2-onemetal complexesbiological activityfluorescent propertiesChemistryQD1-999ENFrontiers in Chemistry, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	coumarin 2H-chromen-2-one metal complexes biological activity fluorescent properties Chemistry QD1-999
spellingShingle	coumarin 2H-chromen-2-one metal complexes biological activity fluorescent properties Chemistry QD1-999 Łukasz Balewski Sylwia Szulta Aleksandra Jalińska Anita Kornicka A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
description	The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has been reported that the incorporation of a metal ion into coumarin derivatives can increase the activity of such complexes compared to coumarin-based ligands. Accordingly, some of them have been found to display promising antioxidant, antitumor or antibacterial activities. This mini-review briefly summarizes the recent development of coumarin-metal complexes with proven biological properties. The attention is also paid to agents for which practical applications in the detection of biologically important species may be found.
format	article
author	Łukasz Balewski Sylwia Szulta Aleksandra Jalińska Anita Kornicka
author_facet	Łukasz Balewski Sylwia Szulta Aleksandra Jalińska Anita Kornicka
author_sort	Łukasz Balewski
title	A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
title_short	A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
title_full	A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
title_fullStr	A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
title_full_unstemmed	A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
title_sort	mini-review: recent advances in coumarin-metal complexes with biological properties
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/e28b27cbd51a4be89cca7b0fbdc1c18d
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A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties

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