A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties
The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has bee...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:e28b27cbd51a4be89cca7b0fbdc1c18d2021-12-01T23:04:45ZA Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties2296-264610.3389/fchem.2021.781779https://doaj.org/article/e28b27cbd51a4be89cca7b0fbdc1c18d2021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fchem.2021.781779/fullhttps://doaj.org/toc/2296-2646The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has been reported that the incorporation of a metal ion into coumarin derivatives can increase the activity of such complexes compared to coumarin-based ligands. Accordingly, some of them have been found to display promising antioxidant, antitumor or antibacterial activities. This mini-review briefly summarizes the recent development of coumarin-metal complexes with proven biological properties. The attention is also paid to agents for which practical applications in the detection of biologically important species may be found.Łukasz BalewskiSylwia SzultaAleksandra JalińskaAnita KornickaFrontiers Media S.A.articlecoumarin2H-chromen-2-onemetal complexesbiological activityfluorescent propertiesChemistryQD1-999ENFrontiers in Chemistry, Vol 9 (2021) |
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coumarin 2H-chromen-2-one metal complexes biological activity fluorescent properties Chemistry QD1-999 |
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coumarin 2H-chromen-2-one metal complexes biological activity fluorescent properties Chemistry QD1-999 Łukasz Balewski Sylwia Szulta Aleksandra Jalińska Anita Kornicka A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties |
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The coumarin nucleus is a recurring motif in both natural and synthetic compounds that exhibit a broad spectrum of biological properties including anticoagulant, anti-inflammatory, antioxidant, antiviral, antimicrobial and anticancer agents as well as enzyme inhibitors. On the other hand, it has been reported that the incorporation of a metal ion into coumarin derivatives can increase the activity of such complexes compared to coumarin-based ligands. Accordingly, some of them have been found to display promising antioxidant, antitumor or antibacterial activities. This mini-review briefly summarizes the recent development of coumarin-metal complexes with proven biological properties. The attention is also paid to agents for which practical applications in the detection of biologically important species may be found. |
format |
article |
author |
Łukasz Balewski Sylwia Szulta Aleksandra Jalińska Anita Kornicka |
author_facet |
Łukasz Balewski Sylwia Szulta Aleksandra Jalińska Anita Kornicka |
author_sort |
Łukasz Balewski |
title |
A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties |
title_short |
A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties |
title_full |
A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties |
title_fullStr |
A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties |
title_full_unstemmed |
A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties |
title_sort |
mini-review: recent advances in coumarin-metal complexes with biological properties |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/e28b27cbd51a4be89cca7b0fbdc1c18d |
work_keys_str_mv |
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