Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria

Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17th century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we de...

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Autores principales:	Alexey Youssef, Samar Yaseer, Rim Harfouch, Maya Marouf, Foz Hasan
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2018
Materias:	chiclero's ulcer cutaneous leishmaniasis leishmania tropica Medicine R
Acceso en línea:	https://doaj.org/article/e2902c702bd6495cb68cbbe8e9c2cd1e
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spelling	oai:doaj.org-article:e2902c702bd6495cb68cbbe8e9c2cd1e2021-12-02T16:35:54ZChiclero's ulcer: An unusual presentation of Leishmania tropica in Syria2231-07702249-446410.4103/ajm.AJM_145_17https://doaj.org/article/e2902c702bd6495cb68cbbe8e9c2cd1e2018-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.AJM_145_17https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17th century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we describe a case of a 67-year-old patient with a 6-month, nonhealing ulcerative lesion of the left auricle. It was initially diagnosed as either a squamous or a basal cell carcinoma. However, the biopsy revealed an unexpected finding of Leishmania amastigotes in the histiocytes. Consequently, CL of the auricle, chiclero's ulcer, was diagnosed. Polymerase chain reaction, in turn, revealed Leishmania tropica to be the causing factor; a rather rare one for chiclero's ulcer. The lesion completely resolved after a 3-week glucantime regimen, without any recurrence after an 8-month follow-up.Alexey YoussefSamar YaseerRim HarfouchMaya MaroufFoz HasanThieme Medical and Scientific Publishers Pvt. Ltd.articlechiclero's ulcercutaneous leishmaniasisleishmania tropicaMedicineRENAvicenna Journal of Medicine, Vol 8, Iss 03, Pp 117-119 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	chiclero's ulcer cutaneous leishmaniasis leishmania tropica Medicine R
spellingShingle	chiclero's ulcer cutaneous leishmaniasis leishmania tropica Medicine R Alexey Youssef Samar Yaseer Rim Harfouch Maya Marouf Foz Hasan Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
description	Cutaneous leishmaniasis (CL) has been an endemic disease in Syria for decades. The first reports of CL from the Syrian city Aleppo date back to the 17th century. The recent crisis has further empowered the spread of this infection not only in Syria, but also in the neighboring countries. Here, we describe a case of a 67-year-old patient with a 6-month, nonhealing ulcerative lesion of the left auricle. It was initially diagnosed as either a squamous or a basal cell carcinoma. However, the biopsy revealed an unexpected finding of Leishmania amastigotes in the histiocytes. Consequently, CL of the auricle, chiclero's ulcer, was diagnosed. Polymerase chain reaction, in turn, revealed Leishmania tropica to be the causing factor; a rather rare one for chiclero's ulcer. The lesion completely resolved after a 3-week glucantime regimen, without any recurrence after an 8-month follow-up.
format	article
author	Alexey Youssef Samar Yaseer Rim Harfouch Maya Marouf Foz Hasan
author_facet	Alexey Youssef Samar Yaseer Rim Harfouch Maya Marouf Foz Hasan
author_sort	Alexey Youssef
title	Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_short	Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_full	Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_fullStr	Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_full_unstemmed	Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
title_sort	chiclero's ulcer: an unusual presentation of leishmania tropica in syria
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2018
url	https://doaj.org/article/e2902c702bd6495cb68cbbe8e9c2cd1e
work_keys_str_mv	AT alexeyyoussef chiclerosulceranunusualpresentationofleishmaniatropicainsyria AT samaryaseer chiclerosulceranunusualpresentationofleishmaniatropicainsyria AT rimharfouch chiclerosulceranunusualpresentationofleishmaniatropicainsyria AT mayamarouf chiclerosulceranunusualpresentationofleishmaniatropicainsyria AT fozhasan chiclerosulceranunusualpresentationofleishmaniatropicainsyria
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Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria

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