SIRT1 accelerates the progression of activity-based anorexia

Anorexia nervosa is an eating disorder characterized by fear of gaining weight that can lead to serious complications. Here the authors show that inhibition of SIRT1 is protective against the onset and progression of anorectic behavior in an activity-based anorexia model, suggesting SIRT1 could be a...

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Autores principales:	Timothy M. Robinette, Justin W. Nicholatos, Adam B. Francisco, Kayla E. Brooks, Rachel Y. Diao, Sandro Sorbi, Valdo Ricca, Benedetta Nacmias, Miguel A. Brieño-Enríquez, Sergiy Libert
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e2920cd71a6c4de88a51804d31fe2360
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spelling	oai:doaj.org-article:e2920cd71a6c4de88a51804d31fe23602021-12-02T17:50:40ZSIRT1 accelerates the progression of activity-based anorexia10.1038/s41467-020-16348-92041-1723https://doaj.org/article/e2920cd71a6c4de88a51804d31fe23602020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16348-9https://doaj.org/toc/2041-1723Anorexia nervosa is an eating disorder characterized by fear of gaining weight that can lead to serious complications. Here the authors show that inhibition of SIRT1 is protective against the onset and progression of anorectic behavior in an activity-based anorexia model, suggesting SIRT1 could be a potential therapeutic target.Timothy M. RobinetteJustin W. NicholatosAdam B. FranciscoKayla E. BrooksRachel Y. DiaoSandro SorbiValdo RiccaBenedetta NacmiasMiguel A. Brieño-EnríquezSergiy LibertNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy M. Robinette Justin W. Nicholatos Adam B. Francisco Kayla E. Brooks Rachel Y. Diao Sandro Sorbi Valdo Ricca Benedetta Nacmias Miguel A. Brieño-Enríquez Sergiy Libert SIRT1 accelerates the progression of activity-based anorexia
description	Anorexia nervosa is an eating disorder characterized by fear of gaining weight that can lead to serious complications. Here the authors show that inhibition of SIRT1 is protective against the onset and progression of anorectic behavior in an activity-based anorexia model, suggesting SIRT1 could be a potential therapeutic target.
format	article
author	Timothy M. Robinette Justin W. Nicholatos Adam B. Francisco Kayla E. Brooks Rachel Y. Diao Sandro Sorbi Valdo Ricca Benedetta Nacmias Miguel A. Brieño-Enríquez Sergiy Libert
author_facet	Timothy M. Robinette Justin W. Nicholatos Adam B. Francisco Kayla E. Brooks Rachel Y. Diao Sandro Sorbi Valdo Ricca Benedetta Nacmias Miguel A. Brieño-Enríquez Sergiy Libert
author_sort	Timothy M. Robinette
title	SIRT1 accelerates the progression of activity-based anorexia
title_short	SIRT1 accelerates the progression of activity-based anorexia
title_full	SIRT1 accelerates the progression of activity-based anorexia
title_fullStr	SIRT1 accelerates the progression of activity-based anorexia
title_full_unstemmed	SIRT1 accelerates the progression of activity-based anorexia
title_sort	sirt1 accelerates the progression of activity-based anorexia
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e2920cd71a6c4de88a51804d31fe2360
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SIRT1 accelerates the progression of activity-based anorexia

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