Structure of the Recombinant <italic toggle="yes">Neisseria gonorrhoeae</italic> Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci

Structure of the Recombinant <italic toggle="yes">Neisseria gonorrhoeae</italic> Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci

ABSTRACT Neisseria gonorrhoeae (gonococcus [Ng]) is the causative organism of the sexually transmitted disease gonorrhoea, and no effective vaccine exists currently. In this study, the structure, biological properties, and vaccine potential of the Ng-adhesin complex protein (Ng-ACP) are presented. T...

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Autores principales: Hannia Liliana Almonacid-Mendoza, María Victoria Humbert, Aiste Dijokaite, David W. Cleary, Yiwen Soo, Miao-Chiu Hung, Christian M. Orr, Moritz M. Machelett, Ivo Tews, Myron Christodoulides
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
NGO1981
Neisseria gonorrhoeae
adhesin complex protein
bactericidal antibody
crystal structure
recombinant protein production
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/e2941d24a855434e9c37e27add646cd8
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