Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C

Linking antibiotic resistance (AR) in the gut microbiome with their bacterial hosts remains challenging. Here, the authors apply bacterial Hi-C to map mobile genetic elements in metagenomes, and illustrate that genes are present in more diverse taxa in neutropenic patients than healthy subjects.

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Autores principales:	Alyssa G. Kent, Albert C. Vill, Qiaojuan Shi, Michael J. Satlin, Ilana Lauren Brito
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e296af1a30b04de1bea63202772c38d8
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spelling	oai:doaj.org-article:e296af1a30b04de1bea63202772c38d82021-12-02T15:25:37ZWidespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C10.1038/s41467-020-18164-72041-1723https://doaj.org/article/e296af1a30b04de1bea63202772c38d82020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18164-7https://doaj.org/toc/2041-1723Linking antibiotic resistance (AR) in the gut microbiome with their bacterial hosts remains challenging. Here, the authors apply bacterial Hi-C to map mobile genetic elements in metagenomes, and illustrate that genes are present in more diverse taxa in neutropenic patients than healthy subjects.Alyssa G. KentAlbert C. VillQiaojuan ShiMichael J. SatlinIlana Lauren BritoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alyssa G. Kent Albert C. Vill Qiaojuan Shi Michael J. Satlin Ilana Lauren Brito Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
description	Linking antibiotic resistance (AR) in the gut microbiome with their bacterial hosts remains challenging. Here, the authors apply bacterial Hi-C to map mobile genetic elements in metagenomes, and illustrate that genes are present in more diverse taxa in neutropenic patients than healthy subjects.
format	article
author	Alyssa G. Kent Albert C. Vill Qiaojuan Shi Michael J. Satlin Ilana Lauren Brito
author_facet	Alyssa G. Kent Albert C. Vill Qiaojuan Shi Michael J. Satlin Ilana Lauren Brito
author_sort	Alyssa G. Kent
title	Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
title_short	Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
title_full	Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
title_fullStr	Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
title_full_unstemmed	Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
title_sort	widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial hi-c
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e296af1a30b04de1bea63202772c38d8
work_keys_str_mv	AT alyssagkent widespreadtransferofmobileantibioticresistancegeneswithinindividualgutmicrobiomesrevealedthroughbacterialhic AT albertcvill widespreadtransferofmobileantibioticresistancegeneswithinindividualgutmicrobiomesrevealedthroughbacterialhic AT qiaojuanshi widespreadtransferofmobileantibioticresistancegeneswithinindividualgutmicrobiomesrevealedthroughbacterialhic AT michaeljsatlin widespreadtransferofmobileantibioticresistancegeneswithinindividualgutmicrobiomesrevealedthroughbacterialhic AT ilanalaurenbrito widespreadtransferofmobileantibioticresistancegeneswithinindividualgutmicrobiomesrevealedthroughbacterialhic
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Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C

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