Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products r...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2015
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/e2974653fda546ac8275eff2e106f57d |
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| Sumario: | The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05). |
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