Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A

The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products r...

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Autores principales: B. Ya. Vlasov, M. A. Rashidova, L. F. Sholokhov, O. A. Vanteeva, E. L. Chudinova
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2015
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Acceso en línea:https://doaj.org/article/e2974653fda546ac8275eff2e106f57d
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spelling oai:doaj.org-article:e2974653fda546ac8275eff2e106f57d2021-11-23T06:14:31ZStatus of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A2541-94202587-9596https://doaj.org/article/e2974653fda546ac8275eff2e106f57d2015-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05).B. Ya. VlasovM. A. RashidovaL. F. SholokhovO. A. VanteevaE. L. ChudinovaScientific Сentre for Family Health and Human Reproduction Problemsarticleviral hepatitis alipid peroxidation - antioxidant protection systemoxidative stresswomenreproductive ageScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 7-10 (2015)
institution DOAJ
collection DOAJ
language RU
topic viral hepatitis a
lipid peroxidation - antioxidant protection system
oxidative stress
women
reproductive age
Science
Q
spellingShingle viral hepatitis a
lipid peroxidation - antioxidant protection system
oxidative stress
women
reproductive age
Science
Q
B. Ya. Vlasov
M. A. Rashidova
L. F. Sholokhov
O. A. Vanteeva
E. L. Chudinova
Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
description The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05).
format article
author B. Ya. Vlasov
M. A. Rashidova
L. F. Sholokhov
O. A. Vanteeva
E. L. Chudinova
author_facet B. Ya. Vlasov
M. A. Rashidova
L. F. Sholokhov
O. A. Vanteeva
E. L. Chudinova
author_sort B. Ya. Vlasov
title Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
title_short Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
title_full Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
title_fullStr Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
title_full_unstemmed Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
title_sort status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis a
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2015
url https://doaj.org/article/e2974653fda546ac8275eff2e106f57d
work_keys_str_mv AT byavlasov statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa
AT marashidova statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa
AT lfsholokhov statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa
AT oavanteeva statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa
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