Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A
The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products r...
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Scientific Сentre for Family Health and Human Reproduction Problems
2015
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oai:doaj.org-article:e2974653fda546ac8275eff2e106f57d2021-11-23T06:14:31ZStatus of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A2541-94202587-9596https://doaj.org/article/e2974653fda546ac8275eff2e106f57d2015-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05).B. Ya. VlasovM. A. RashidovaL. F. SholokhovO. A. VanteevaE. L. ChudinovaScientific Сentre for Family Health and Human Reproduction Problemsarticleviral hepatitis alipid peroxidation - antioxidant protection systemoxidative stresswomenreproductive ageScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 7-10 (2015) |
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DOAJ |
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RU |
topic |
viral hepatitis a lipid peroxidation - antioxidant protection system oxidative stress women reproductive age Science Q |
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viral hepatitis a lipid peroxidation - antioxidant protection system oxidative stress women reproductive age Science Q B. Ya. Vlasov M. A. Rashidova L. F. Sholokhov O. A. Vanteeva E. L. Chudinova Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
description |
The objective of this study was to identify features of the system of lipid peroxidation - antioxidant protection in 31 women of reproductive age with viral hepatitis A. In women with hepatitis A virus (HAV) (main group) there is an increase in the level of double bonds (31,1%) and active products reacting with thiobarbituric acid (141,7%) with a simultaneous decrease in the content of diene conjugates (69,4%), compared with the same indicators in the control group. The level of antioxidant protection in women in main group unlike the control was characterized by a decrease in total antioxidant activity (25,2%), by the inhibition of the activity of superoxide dismutase (29,1%), by decreasing the concentration of a-tocopherol (42,6%) on the background of increase of retinol level (184,6%). In general, the combination of prooxidant and antioxidant factors at HAV can be considered as a condition of oxidative stress (p < 0,05). |
format |
article |
author |
B. Ya. Vlasov M. A. Rashidova L. F. Sholokhov O. A. Vanteeva E. L. Chudinova |
author_facet |
B. Ya. Vlasov M. A. Rashidova L. F. Sholokhov O. A. Vanteeva E. L. Chudinova |
author_sort |
B. Ya. Vlasov |
title |
Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
title_short |
Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
title_full |
Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
title_fullStr |
Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
title_full_unstemmed |
Status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis A |
title_sort |
status of lipid peroxidation and antioxidant protection system in women of reproductive age with viral hepatitis a |
publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
publishDate |
2015 |
url |
https://doaj.org/article/e2974653fda546ac8275eff2e106f57d |
work_keys_str_mv |
AT byavlasov statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa AT marashidova statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa AT lfsholokhov statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa AT oavanteeva statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa AT elchudinova statusoflipidperoxidationandantioxidantprotectionsysteminwomenofreproductiveagewithviralhepatitisa |
_version_ |
1718417103209365504 |